Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 4/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAX | P61244 | 2/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358730 | 0.91 | AKR1C2 (0.62) | AKR1C2AKR1C1MAPTKMT2AMEN1 | |
| SCHEMBL6359133 | 0.87 | AKR1C2 (0.68) | AKR1C2AKR1C1MAPTKMT2AMEN1 | |
| SCHEMBL6358257 | 0.83 | MAOB (0.58) | AKR1C2AKR1C1MAPTKMT2AMEN1 | |
| SCHEMBL4211236 | 0.81 | MAPT (0.59) | AKR1C2AKR1C1MAPTKMT2AMEN1 | |
| SCHEMBL6353682 | 0.81 | AKR1C2 (0.71) | AKR1C2AKR1C1MAPTKMT2AMEN1 | |
| SCHEMBL4209179 | 0.81 | AKR1C2 (0.56) | AKR1C2AKR1C1MAPTKMT2AMEN1 | |
| SCHEMBL4213146 | 0.80 | AKR1C2 (0.61) | AKR1C2AKR1C1MAPTKMT2AMEN1 | |
| SCHEMBL6351828 | 0.78 | PTGES (0.62) | AKR1C2AKR1C1MAPTKMT2AMEN1 | |
| SCHEMBL6353035 | 0.78 | PKM (0.67) | AKR1C2AKR1C1MAPTKMT2AMEN1 | |
| SCHEMBL6349641 | 0.77 | PLK1 (0.60) | AKR1C2AKR1C1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885MAPT 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.