Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | METAP2 | P50579 | 2/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SLC10A6 | Q3KNW5 | 2/20 | 0.52 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.52 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352359 | 0.89 | METAP2 (0.71) | RPA1KMT2AMEN1METAP2SLC10A6 | |
| SCHEMBL6358095 | 0.89 | MEN1 (0.60) | RPA1KMT2AMEN1METAP2LMNA | |
| SCHEMBL6349460 | 0.88 | MEN1 (0.60) | RPA1KMT2AMEN1METAP2SLC10A6 | |
| SCHEMBL6350610 | 0.86 | MEN1 (0.69) | RPA1KMT2AMEN1METAP2GFER | |
| SCHEMBL6348358 | 0.85 | METAP2 (0.71) | RPA1KMT2AMEN1METAP2SLC10A6 | |
| SCHEMBL4100021 | 0.82 | MEN1 (0.74) | KMT2AMEN1METAP2SLC10A6SLC10A2 | |
| SCHEMBL1308635 | 0.82 | AKR1C2 (0.65) | RPA1KMT2AMEN1KCNK2KCNK10 | |
| SCHEMBL4105084 | 0.82 | MEN1 (0.84) | RPA1KMT2AMEN1GFERALDH1A1 | |
| SCHEMBL6346651 | 0.81 | METAP2 (0.65) | KMT2AMEN1METAP2MIFTP53 | |
| SCHEMBL7066756 | 0.81 | KCNK2 (0.47) | RPA1KMT2AMEN1METAP2SLC10A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | RPA1 3847/4885KMT2A 3645/4885MEN1 3274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.