SCHEMBL6353755

SCHEMBL6353755

Nc1ccc(S(=O)(=O)CCCl)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.57
TSHR P16473 4/20 0.50
CYP3A4 P08684 3/20 0.50
CYP2C9 P11712 2/20 0.50
LMNA P02545 1/20 0.50
MPO P05164 1/20 0.50
HTR6 P50406 1/20 0.50
CA2 P00918 10/20 0.48
CA1 P00915 7/20 0.48
CA12 O43570 6/20 0.48
CA9 Q16790 6/20 0.48
CA14 Q9ULX7 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
USP2 O75604 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA13 Q8N1Q1 1/20 0.48
AGO2 Q9UKV8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11375991 0.82 GAA (0.61) GAATSHRCYP3A4CYP2C9LMNA
SCHEMBL29980399 0.82 GAA (0.61) GAATSHRCYP3A4CYP2C9LMNA
SCHEMBL9352902 0.80 CA2 (0.58) TSHRHTR6CA2CA1CA12
SCHEMBL10702964 0.80 GAA (0.59) GAATSHRCYP3A4CYP2C9LMNA
SCHEMBL426162 0.80 ALDH1A1 (0.52) GAACYP3A4CYP2C9LMNACA2
SCHEMBL9352809 0.79 PSIP1 (0.62) CYP3A4CYP2C9CA2CA1CA12
SCHEMBL8775111 0.78 ALDH1A1 (0.42) GAACYP3A4CYP2C9LMNACA2
SCHEMBL1149166 0.78 ALDH1A1 (0.69) GAACYP3A4CYP2C9LMNACA2
SCHEMBL2148822 0.78 CA2 (0.70) GAATSHRCYP3A4CYP2C9LMNA
SCHEMBL3514586 0.78 PLCG1 (0.61) CYP3A4CYP2C9LMNACA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050203286-A1 Environmental protection series of reactive dyestuffs and their use EVERLIGHT USA, INC. (US) 2005-09-15 US disclosed
EP-0574799-B1 Method for the preparation of fibre-reactive formazana dyes as well as aminophenols BASF AG (DE) 1997-09-17 EP disclosed
EP-0497174-B1 Bifunctional reactive dyes containing vinylsulfone/pyrimidine groups BAYER AG (DE) 1997-03-05 EP disclosed
EP-0567793-B1 Water-soluble azocompounds, process for their manufacture and their use as dyes HOECHST AG (DE) 1996-10-23 EP disclosed
US-5536876-A Formylamino-aminophenol compounds and their use in preparation of fiber-reactive formazan dyes BASF AKTIENGESELLSCHAFT (DE) 1996-07-16 US disclosed
US-5514782-A Phenyl-azo-aminophenyl compounds substituted by an aminosubstituted fluoro-triazinylamino group and a fibre-reactive group of the vinylsulfone series HOECHST AKTIENGESELLSCHAFT (DE) 1996-05-07 US disclosed
US-5463031-A Printing, dyeing cellulose and organonitrogen compounds BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed
US-5410027-A Diazotization of a protectively formylated hydroxyphenylenediamine; coupling with a hydrazone compound; metallization; reacting with a halotriazine BASF AKTIENGESELLSCHAFT (DE) 1995-04-25 US disclosed
EP-0432542-B1 Azo dyestuffs and intermediates for their preparation BAYER AG (DE) 1994-09-14 EP disclosed
EP-0395951-B1 Polyfunctional reactive dyes BAYER AG (DE) 1994-08-24 EP disclosed
US-4652634-A Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-24 US disclosed
US-4649193-A COTTON, WOOL, POLYAMIDES; COLOR-AND WASH FASTNESS HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-10 US disclosed
EP-0119441-B1 REACTIVE DYES WITH SUBSTITUTED 4-FLUOROPYRIDAZ-6-ONE GROUPS BASF Aktiengesellschaft (DE) 1987-02-25 EP disclosed
US-4576755-A Water-soluble fibre-reactive phthalocyanine compounds HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-18 US disclosed
EP-0119441-A2 Reactive dyes with substituted 4-fluoropyridaz-6-one groups BASF Aktiengesellschaft (DE) 1984-09-26 EP disclosed
US-4430259-A Water-soluble disazo compounds suitable as fiber-reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1984-02-07 US disclosed
US-4350632-A FIBER-REACTIVE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-21 US disclosed
US-4252529-A AMINOPHENOL OR AMINONAPHTHOL COMPOUND WITH SUBSTITUTED FIBER-REACTIVE RADICAL HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-24 US disclosed
US-4242258-A TETRAKISAZO, BLACK HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-30 US disclosed
US-3957751-A WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed