SCHEMBL1149166

SCHEMBL1149166

Cc1ccc(S(=O)(=O)CCCl)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.69
CYP2C19 P33261 2/20 0.69
CYP3A4 P08684 1/20 0.69
CYP2C9 P11712 1/20 0.69
KMT2A Q03164 8/20 0.53
NPC1 O15118 1/20 0.53
GAA P10253 3/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
PAX8 Q06710 1/20 0.47
CTSK P43235 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6331035 0.88 ALDH1A1 (0.77) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL41372 0.86 ALDH1A1 (0.82) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL2734649 0.86 ALDH1A1 (0.74) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL2733252 0.84 ALDH1A1 (0.71) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL2734665 0.84 ALDH1A1 (0.71) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL23674957 0.84 ALDH1A1 (0.71) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL2734249 0.84 ALDH1A1 (0.71) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL1820762 0.82 ALDH1A1 (1.00) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL1149248 0.82 ALDH1A1 (0.61) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A
SCHEMBL1582969 0.82 ALDH1A1 (0.91) ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118763273-A Sulfonyl deep eutectic polymer electrolyte and preparation and application thereof 青岛赛锂达储能产业技术研究院有限公司 2024-10-11 CN claimed
CN-104531397-A Cleaning solution for sheet glass substrate thinning pre-cleaning, and application thereof HUIJING DISPLAY TECHNOLOGY SUZHOU CO LTD 2015-04-22 CN claimed
CN-118763273-A Sulfonyl deep eutectic polymer electrolyte and preparation and application thereof 青岛赛锂达储能产业技术研究院有限公司 2024-10-11 CN disclosed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 US disclosed
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2020-05-26 US disclosed
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2019-10-08 US disclosed
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2018-08-02 US disclosed
EP-3315531-A1 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY Xiamen Sinopeg Biotech Co., Ltd. (CN) 2018-05-02 EP disclosed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US disclosed
CN-104531397-A Cleaning solution for sheet glass substrate thinning pre-cleaning, and application thereof HUIJING DISPLAY TECHNOLOGY SUZHOU CO LTD 2015-04-22 CN disclosed
US-20140221323-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2014-08-07 US disclosed
US-5902905-A Method for producing arylvinylsulfone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-05-11 US disclosed
WO-1998039316-A1 N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS MONSANTO COMPANY (US) 1998-09-11 WO disclosed
EP-0841323-A2 Method for producing arylvinylsulfone SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-05-13 EP disclosed
US-5716936-A Pyrrolidine derivatives for the treatment of cholecystokinine and gastrine-related disorders RHONE-POULENC RORER S.A. (FR) 1998-02-10 US disclosed
WO-1997042144-A1 PROCESS FOR THE ALKYLATION OF A CYCLOPENTADIENE DSM N.V. (NL) 1997-11-13 WO disclosed
WO-1997042143-A1 PROCESS FOR THE PREPARATION OF A SPIRO[2.4]-HEPTA-4,6-DIENE DSM N.V. (NL) 1997-11-13 WO disclosed
EP-0182299-B1 A CURABLE FLUOROELASTOMER COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-04-03 EP disclosed
US-4748208-A FLUOROPOLYMER, BIS/PHOSPHINE/IMINIUM HALIDE, POLYHYDROXY CURING AGENT ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-05-31 US disclosed
EP-0182299-A2 A curable fluoroelastomer composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, MRPS18A ALDH1A1 1103/4885CYP2C19 3704/4885CYP3A4 1434/4885
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, COG8 ALDH1A1 787/4885CYP2C19 2999/4885CYP3A4 1205/4885
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF MRPL38, CXCL8, ALG8 ALDH1A1 1061/4885CYP2C19 2853/4885CYP3A4 1259/4885
US-20140221323-A1 FATTY ACID ACETYLATED SALICYLATES AND THEIR USES FASN, ACACA, FABP4 ALDH1A1 285/4885CYP2C19 3252/4885CYP3A4 2855/4885
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 ALDH1A1 1582/4885CYP2C19 3458/4885CYP3A4 2743/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 ALDH1A1 1582/4885CYP2C19 3458/4885CYP3A4 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.