Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.66 |
| ▸ | DHODH | Q02127 | 1/20 | 0.63 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353963 | 0.92 | KMT2A (0.62) | SERPINE1DHODHALBKMT2AMAPT | |
| SCHEMBL6359401 | 0.90 | ALB (0.63) | SERPINE1ALBNPC1RAB9AKMT2A | |
| SCHEMBL6349987 | 0.90 | ALB (0.57) | SERPINE1DHODHIGF2BP2ALBNPC1 | |
| SCHEMBL6346687 | 0.88 | ALB (0.60) | SERPINE1ALBRAB9AKMT2AMAPT | |
| SCHEMBL6357270 | 0.88 | SERPINE1 (0.62) | SERPINE1DHODHIGF2BP2ALBKMT2A | |
| SCHEMBL6834385 | 0.86 | SERPINE1 (0.51) | SERPINE1DHODHIGF2BP2ALBPDCD1 | |
| SCHEMBL6350083 | 0.86 | SERPINE1 (0.68) | SERPINE1IGF2BP2ALBNPC1RAB9A | |
| SCHEMBL6833755 | 0.86 | KCNH2 (0.55) | SERPINE1DHODHIGF2BP2ALBKMT2A | |
| SCHEMBL6348543 | 0.85 | ALB (0.58) | SERPINE1ALBKMT2AMAPTMEN1 | |
| SCHEMBL6352338 | 0.85 | KMT2A (0.57) | DHODHALBNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | SERPINE1 1929/4885DHODH 49/4885IGF2BP2 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.