Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788933 | 0.92 | G6PD (0.37) | MAPTL3MBTL1GAAKDM4EHPGD | |
| SCHEMBL7788925 | 0.90 | MAPT (0.40) | MAPTRAB9ASMN1; SMN2SLC2A1CYP1A2 | |
| SCHEMBL635407 | 0.89 | MAPT (0.49) | MAPTL3MBTL1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29560409 | 0.89 | MAPT (0.49) | MAPTL3MBTL1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7806778 | 0.87 | KMT2A (0.36) | SLC2A1DRD2KMT2A | |
| SCHEMBL17080387 | 0.86 | FABP1 (0.40) | MAPTRAB9ASMN1; SMN2GAATDP1 | |
| SCHEMBL23581680 | 0.85 | MAPT (0.41) | MAPTL3MBTL1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31338576 | 0.83 | ALDH1A1 (0.39) | MAPTL3MBTL1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3811084 | 0.82 | MAPT (0.43) | MAPTRAB9ASMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL7518681 | 0.82 | MAPT (0.42) | MAPTL3MBTL1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647647-B1 | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5523437-A | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0647647-A1 | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-12 | — | — | EP | disclosed |