Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 7/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 5/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346459 | 0.97 | GRIA4 (0.36) | GRIA4MMP13ADAM17KCNH2ALDH1A1 | |
| SCHEMBL6410380 | 0.96 | GRIA4 (0.34) | GRIA4MMP13ADAM17KCNH2MMP2 | |
| SCHEMBL6355076 | 0.85 | MEN1 (0.34) | MMP13ADAM17ALDH1A1LMNAGAA | |
| SCHEMBL6356775 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNAGAAGLAMMP3 | |
| SCHEMBL6345585 | 0.84 | SLC6A4 (0.43) | ALDH1A1KMT2AATM | |
| SCHEMBL6244911 | 0.84 | SLC6A4 (0.43) | ALDH1A1KMT2AATM | |
| SCHEMBL6357784 | 0.84 | SLC6A4 (0.43) | ALDH1A1KMT2AATM | |
| SCHEMBL6349722 | 0.84 | KDM4E (0.37) | KCNH2ALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL6356732 | 0.83 | ADAM17 (0.46) | GRIA4MMP13ADAM17KCNH2MMP2 | |
| SCHEMBL6348250 | 0.83 | RORC (0.44) | MMP13ADAM17MMP2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900353-B2 | Cyclopentyl sulfonamide derivatives | ELI LILLY AND COMPANY (US) | 2005-05-31 | — | — | US | disclosed |
| US-20040067984-A1 | Cyclopentyl sulfonamide derivatives | CANTRELL BUDDY EUGENE (US) | 2004-04-08 | — | — | US | disclosed |
| EP-1334087-A1 | CYCLOALKYLFLUOROSULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032858-A1 | CYCLOALKYLFLUOROSULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067984-A1 | Cyclopentyl sulfonamide derivatives | GRIN2A, GRIN1, GRIK5 | GRIA4 15/4885MMP13 4862/4885ADAM17 3636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.