Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.58 |
| ▸ | PPARD | Q03181 | 12/20 | 0.58 |
| ▸ | PPARA | Q07869 | 11/20 | 0.58 |
| ▸ | CPT1A | P50416 | 5/20 | 0.51 |
| ▸ | CPT1B | Q92523 | 5/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | CPT2 | P23786 | 3/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352803 | 0.84 | CPT1A (0.49) | PPARGPPARDPPARACPT1ACPT1B | |
| SCHEMBL6359987 | 0.82 | PPARG (0.65) | PPARGPPARDPPARACPT1ACPT1B | |
| SCHEMBL6358782 | 0.81 | PPARG (0.64) | PPARGPPARDPPARAALBTNF | |
| SCHEMBL6353192 | 0.81 | PPARG (0.62) | PPARGPPARDPPARACPT1ACPT1B | |
| SCHEMBL6357317 | 0.79 | ALB (0.53) | PPARGPPARDPPARAALB | |
| SCHEMBL6346544 | 0.78 | PPARG (0.66) | PPARGPPARDPPARAALBTNF | |
| SCHEMBL6351428 | 0.78 | PPARG (0.65) | PPARGPPARDPPARAALBTNF | |
| SCHEMBL6351239 | 0.78 | PPARG (0.65) | PPARGPPARDPPARAALBTNF | |
| SCHEMBL6356719 | 0.77 | PPARG (0.64) | PPARGPPARDPPARAALBTNF | |
| SCHEMBL6349468 | 0.77 | PPARG (0.57) | PPARGPPARDPPARAALBTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | PPARG 3572/4885PPARD 2519/4885PPARA 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.