Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL8045384 | 0.84 | CA2 (0.46) | CA2KIF11ALDH1A1ATML3MBTL1 | |
| Valine SCHEMBL8045567 | 0.84 | CA2 (0.46) | CA2KIF11ALDH1A1ATML3MBTL1 | |
| Valine SCHEMBL8035685 | 0.84 | CA2 (0.46) | CA2KIF11ALDH1A1ATML3MBTL1 | |
| SCHEMBL6357306 | 0.83 | CYP2D6 (0.47) | CA2KIF11ALDH1A1L3MBTL1GAA | |
| SCHEMBL6357928 | 0.83 | TSHR (0.55) | KIF11ALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL6362798 | 0.82 | SLC1A3 (0.46) | CA2KIF11ALDH1A1TSHRNT5E | |
| SCHEMBL1563242 | 0.79 | CA2 (0.61) | CA2ALDH1A1L3MBTL1AKR1C3TAS2R14 | |
| SCHEMBL93796 | 0.79 | CA2 (0.61) | CA2ALDH1A1L3MBTL1AKR1C3TAS2R14 | |
| Isoleucine SCHEMBL8036378 | 0.78 | CA2 (0.44) | CA2KIF11ALDH1A1ATML3MBTL1 | |
| Leucine SCHEMBL8047098 | 0.78 | SLC7A5 (0.51) | CA2KIF11ALDH1A1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107473-A1 | Process for producing tert-leucine | AJINOMOTO CO. INC (JP) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107473-A1 | Process for producing tert-leucine | TERT, LRRK2, BCAT1 | CA2 3422/4885KIF11 3164/4885ALDH1A1 1392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.