Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157675 | 0.66 | DHFR (0.42) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6358271 | 0.66 | LMNA (0.32) | LMNANPSR1 | |
| SCHEMBL6358274 | 0.66 | LMNA (0.32) | LMNANPSR1 | |
| SCHEMBL6359199 | 0.64 | S1PR4 (0.45) | HPGDNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6360528 | 0.64 | MCOLN3 (0.34) | THRATHRB | |
| SCHEMBL6360529 | 0.64 | MCOLN3 (0.34) | THRATHRB | |
| SCHEMBL28602974 | 0.62 | — | — | |
| SCHEMBL6357689 | 0.62 | LMNA (0.31) | LMNAALDH1A1NPSR1 | |
| SCHEMBL6357690 | 0.62 | LMNA (0.31) | LMNAALDH1A1NPSR1 | |
| SCHEMBL6363621 | 0.62 | MAOB (0.33) | LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182025-A1 | Amidinylphenyl compounds and their use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182025-A1 | Amidinylphenyl compounds and their use as fungicides | OR10J3, CBR3, C3AR1 | CYSLTR2 1629/4885CYSLTR1 1180/4885TSHR 593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.