Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357707 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBTDP1LMNAHTT | |
| SCHEMBL6356821 | 1.00 | ALDH1A1 (0.43) | ALDH1A1POLBTDP1LMNAHTT | |
| SCHEMBL6357306 | 0.83 | CYP2D6 (0.47) | ALDH1A1TDP1LMNAHTTKIF11 | |
| SCHEMBL6357842 | 0.81 | CASR (0.43) | ALDH1A1TDP1KIF11CASRTSHR | |
| SCHEMBL6357928 | 0.80 | TSHR (0.55) | ALDH1A1POLBTDP1KIF11CASR | |
| SCHEMBL6362798 | 0.79 | SLC1A3 (0.46) | ALDH1A1KIF11TSHRCA2 | |
| SCHEMBL83885 | 0.79 | LMNA (0.61) | ALDH1A1TDP1LMNAHTTPKM | |
| SCHEMBL30487906 | 0.79 | LMNA (0.61) | ALDH1A1TDP1LMNAHTTPKM | |
| SCHEMBL8715253 | 0.77 | LMNA (0.59) | ALDH1A1TDP1LMNAHTTPKM | |
| SCHEMBL6913755 | 0.77 | LMNA (0.59) | ALDH1A1TDP1LMNAHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107473-A1 | Process for producing tert-leucine | AJINOMOTO CO. INC (JP) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107473-A1 | Process for producing tert-leucine | TERT, LRRK2, BCAT1 | ALDH1A1 1392/4885POLB 839/4885TDP1 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.