Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.48 |
| ▸ | CTSL | P07711 | 14/20 | 0.48 |
| ▸ | CTSS | P25774 | 13/20 | 0.48 |
| ▸ | CTSB | P07858 | 5/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6355388 | 0.82 | CTSK (0.39) | CTSKCTSLCTSS | |
| SCHEMBL6356868 | 0.81 | CTSK (0.38) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6258945 | 0.77 | CTSL (0.49) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL21067433 | 0.74 | CTSK (0.68) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4171722 | 0.74 | CTSK (0.68) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4323805 | 0.72 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4310385 | 0.72 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4312951 | 0.72 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL3934296 | 0.72 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4316429 | 0.72 | CTSK (0.69) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256105-A1 | Cysteine protease and serine protease inhibitors; arthritis, parasite infections, osteoporosis, gingivitis; e.g. benzofuran-2-carboxylic acid [(S)-1-((S)-1-cyclohexylmethyl-3,7-dioxo-azepan-4-ylcarbamoyl)-3-methyl-butyl]-amide | JEONG JAE U | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256105-A1 | Cysteine protease and serine protease inhibitors; arthritis, parasite infections, osteoporosis, gingivitis; e.g. benzofuran-2-carboxylic acid [(S)-1-((S)-1-cyclohexylmethyl-3,7-dioxo-azepan-4-ylcarbamoyl)-3-methyl-butyl]-amide | PRSS1, SPINT2, CTRL | CTSK 39/4885CTSL 37/4885CTSS 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.