Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 20/20 | 0.49 |
| ▸ | CTSK | P43235 | 20/20 | 0.49 |
| ▸ | CTSS | P25774 | 19/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258943 | 0.84 | CTSL (0.40) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL3934296 | 0.81 | CTSK (0.69) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL4323805 | 0.81 | CTSK (0.69) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL4312951 | 0.81 | CTSK (0.69) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL4310385 | 0.81 | CTSK (0.69) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL4316429 | 0.81 | CTSK (0.69) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL6256605 | 0.81 | CTSK (0.46) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL6237797 | 0.79 | CTSL (0.43) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL6356870 | 0.77 | CTSK (0.48) | CTSLCTSKCTSSCTSBCTSV | |
| SCHEMBL4319024 | 0.76 | CTSK (0.45) | CTSLCTSKCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005013909-A2 | NOVEL CATHEPSIN K INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-17 | — | — | WO | disclosed |