Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.71 |
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | SPR | P35270 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353748 | 0.89 | DRD4 (0.57) | DRD4DRD2KMT2AALDH1A1LMNA | |
| SCHEMBL6359020 | 0.88 | DRD4 (0.69) | DRD4DRD2HSD11B1KMT2AALDH1A1 | |
| SCHEMBL6352829 | 0.83 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL6352831 | 0.83 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL6357823 | 0.83 | ALDH1A1 (0.69) | DRD4DRD2HSD11B1KMT2AALDH1A1 | |
| SCHEMBL6357751 | 0.80 | DRD4 (0.47) | DRD4DRD2KMT2AALDH1A1LMNA | |
| SCHEMBL12123666 | 0.78 | HTR1A (0.50) | DRD4DRD2KMT2AALDH1A1LMNA | |
| SCHEMBL6350324 | 0.74 | DRD4 (0.84) | DRD4DRD2 | |
| SCHEMBL6350322 | 0.74 | DRD4 (0.84) | DRD4DRD2 | |
| SCHEMBL28602903 | 0.74 | DRD4 (0.50) | DRD4DRD2HTR1AHTR7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | CYP19A1, SHBG, CYP17A1 | DRD4 1272/4885DRD2 1704/4885HSD11B1 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.