Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD5 | P21918 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348925 | 0.91 | ALDH1A1 (0.82) | ALDH1A1KMT2ALMNAGAASIGMAR1 | |
| SCHEMBL6353997 | 0.88 | ALDH1A1 (0.69) | ALDH1A1KMT2ALMNAGAASIGMAR1 | |
| SCHEMBL6357372 | 0.83 | DRD4 (0.71) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL6349352 | 0.81 | DRD4 (0.73) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL6349350 | 0.81 | DRD4 (0.73) | ALDH1A1KMT2ALMNAGAADRD2 | |
| SCHEMBL6357751 | 0.78 | DRD4 (0.47) | ALDH1A1KMT2ALMNAGAASIGMAR1 | |
| Hydrochloric Acid SCHEMBL5954525 | 0.77 | ALDH1A1 (0.72) | ALDH1A1KMT2ALMNASIGMAR1DRD2 | |
| SCHEMBL17033397 | 0.77 | ALDH1A1 (0.72) | ALDH1A1KMT2ALMNASIGMAR1DRD4 | |
| SCHEMBL14587419 | 0.76 | SIGMAR1 (1.00) | ALDH1A1KMT2ALMNAGAASIGMAR1 | |
| Hydrochloric Acid SCHEMBL5954595 | 0.76 | ALDH1A1 (0.71) | ALDH1A1KMT2ALMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176727-A1 | Oximes and hydrazones that are useful in treating sexual dysfunction | CYP19A1, SHBG, CYP17A1 | ALDH1A1 199/4885KMT2A 1762/4885LMNA 4720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.