Sulfuric Acid

Sulfuric Acid

SCHEMBL6357625

COc1cc(Nc2ccccc2)ccc1[N+]#N.O=S(=O)(O)O

nearest known ligand 0.47

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
PPARG P37231 1/20 0.47
PPARD Q03181 1/20 0.47
PPARA Q07869 1/20 0.47
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
SNCA P37840 1/20 0.43
MTNR1B P49286 4/20 0.41
MTNR1A P48039 2/20 0.41
STK10 O94804 1/20 0.40
SLK Q9H2G2 1/20 0.40
LMNA P02545 1/20 0.40
ALOX12 P18054 1/20 0.40
TNNI3 P19429 1/20 0.39
TNNT2 P45379 1/20 0.39
TNNC1 P63316 1/20 0.39
HKDC1 Q2TB90 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL5698877 0.95 MEN1 (0.45) MEN1KMT2APPARGPPARDPPARA
Sulfuric Acid SCHEMBL1123017 0.92 PPARG (0.44) MEN1KMT2APPARGPPARDPPARA
SCHEMBL92096 0.92 MEN1 (0.47) MEN1KMT2APPARGPPARDPPARA
Sulfuric Acid SCHEMBL6929881 0.91 PPARG (0.43) MEN1KMT2APPARGPPARDPPARA
Hydrochloric Acid SCHEMBL8080600 0.90 MEN1 (0.46) MEN1KMT2APPARGPPARDPPARA
Bromide SCHEMBL9172630 0.90 MEN1 (0.46) MEN1KMT2APPARGPPARDPPARA
Hydrochloric Acid SCHEMBL11066823 0.89 MEN1 (0.45) MEN1KMT2APPARGPPARDPPARA
Phosphoric Acid SCHEMBL8777433 0.87 MEN1 (0.48) MEN1KMT2APPARGPPARDPPARA
Sulfuric Acid SCHEMBL9703161 0.86 PPARG (0.42) MEN1KMT2APPARGPPARDPPARA
SCHEMBL1764456 0.86 PPARG (0.43) MEN1KMT2APPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104035279-A Positive infrared sensitive composition and imaging element thereof ZHEJIANG KONITA NEW MATERIALS CO LTD 2014-09-10 CN disclosed
US-20050277053-A1 Increased sensitivity, IR, and UV imageable photographic elements ANOCOIL CORPORATION 2005-12-15 US disclosed
US-20050277051-A1 Increased sensitivity, UV imageable photographic elements ANOCOIL CORPORATION 2005-12-15 US disclosed
US-5637441-A MULTILAYER; ALUMINUM, OR ALLOY THEREOF, AND HYDROPHILIC POLYMER AGFA-GEVAERT AG (DE) 1997-06-10 US disclosed
US-4486529-A WAVELENGTH GREATER THAN 450 NANOMETERS AMERICAN HOECHST CORPORATION (US) 1984-12-04 US disclosed
US-4248959-A Preparation of diazo printing plates using laser exposure AMERICAN HOECHST CORPORATION (US) 1981-02-03 US disclosed