Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 8/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293184 | 0.88 | MAPT (0.49) | MAPTAKR1C3APEX1RXRARXRB | |
| SCHEMBL6357913 | 0.87 | MAPT (0.38) | MAPTAKR1C3 | |
| SCHEMBL16178525 | 0.79 | PTGS1 (0.32) | AKR1C3 | |
| SCHEMBL476070 | 0.79 | PTGS1 (0.32) | AKR1C3 | |
| SCHEMBL17420014 | 0.77 | AKR1C3 (0.44) | MAPTAKR1C3APEX1RXRARXRB | |
| SCHEMBL4917439 | 0.77 | AKR1C3 (0.44) | MAPTAKR1C3APEX1RXRARXRB | |
| SCHEMBL6270241 | 0.76 | MAPT (0.39) | MAPTAKR1C3APEX1CYP2C9RECQL | |
| SCHEMBL3784329 | 0.75 | ALDH1A1 (0.38) | MAPTAKR1C3RXRARXRBNR4A2 | |
| SCHEMBL3787971 | 0.74 | MAPT (0.49) | MAPTAKR1C3APEX1RXRARXRB | |
| SCHEMBL3297070 | 0.72 | AKR1C3 (0.50) | MAPTAKR1C3APEX1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256235-A1 | Stabilized environmentally sensitive binders | ARKEMA INC. | 2005-11-17 | — | — | US | disclosed |