Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 8/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357912 | 0.88 | MAPT (0.41) | MAPTAKR1C3RXRARXRBNR4A2 | |
| SCHEMBL3784329 | 0.85 | ALDH1A1 (0.38) | MAPTAKR1C3RXRARXRBNR4A2 | |
| SCHEMBL3787971 | 0.84 | MAPT (0.49) | MAPTAKR1C3RXRARXRBNR4A2 | |
| SCHEMBL3297070 | 0.82 | AKR1C3 (0.50) | MAPTAKR1C3RXRARXRBNR4A2 | |
| SCHEMBL5144091 | 0.82 | AKR1C3 (0.50) | MAPTAKR1C3RXRARXRBNR4A2 | |
| SCHEMBL17420014 | 0.76 | AKR1C3 (0.44) | MAPTAKR1C3RXRARXRBNR4A2 | |
| SCHEMBL4917439 | 0.76 | AKR1C3 (0.44) | MAPTAKR1C3RXRARXRBNR4A2 | |
| SCHEMBL560335 | 0.76 | AKR1C3 (0.44) | MAPTAKR1C3RXRARXRBNR4A2 | |
| SCHEMBL6270241 | 0.76 | MAPT (0.39) | MAPTAKR1C3CES2CES1CYP2C9 | |
| SCHEMBL6357913 | 0.74 | MAPT (0.38) | MAPTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935288-A1 | SILYL ESTER COPOLYMER | Jotun A/S (NO) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014096102-A1 | SILYL ESTER COPOLYMER | JOTUN A/S (NO) | 2014-06-26 | — | — | WO | disclosed |
| US-20100183540-A1 | BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER | JOTUN A/S (NO) | 2010-07-22 | — | — | US | disclosed |
| US-7736634-B2 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2010-06-15 | — | — | US | disclosed |
| US-7297727-B2 | Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions | ARKEMA INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-20070196326-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | SIGMA COATINGS B.V. (NL) | 2007-08-23 | — | — | US | disclosed |
| US-20060189708-A1 | Benzylsilyl(meth)acryloyl-containing polymers for marine coating compositions | ARKEMA INC. | 2006-08-24 | — | — | US | disclosed |
| EP-1479737-B1 | Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions | ARKEMA INC (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005110440-A1 | STABILIZERS FOR HYDROLYZABLE ORGANIC BINDERS | ARKEMA, INC. (US) | 2005-11-24 | — | — | WO | disclosed |
| US-20050255081-A1 | Stabilizers for hydrolyzable organic binders | ARKEMA INC. | 2005-11-17 | — | — | US | disclosed |
| US-20050014963-A1 | Process for the preparation of organosilylated carboxylate monomers, and their use in antifouling coatings | SIGMA COATINGS B.V. (NL) | 2005-01-20 | — | — | US | disclosed |
| EP-1479737-A1 | Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions | Atofina Chemicals, Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040138332-A1 | Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions | ARKEMA INC. | 2004-07-15 | — | — | US | disclosed |
| US-20030225184-A1 | Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions | ARKEMA INC. | 2003-12-04 | — | — | US | disclosed |
| EP-1367100-A1 | Triarylsilyl (meth) acryloyl-containing polymers for marine coating compositions | ATOFINA CHEMICALS, INC. (US) | 2003-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014963-A1 | Process for the preparation of organosilylated carboxylate monomers, and their use in antifouling coatings | ACMSD, MMAB, GFER | MAPT 3107/4885AKR1C3 948/4885RXRA 3567/4885 |
| US-20070196326-A1 | Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof | PRMT9, MRPL9, CD59 | MAPT 4846/4885AKR1C3 114/4885RXRA 2058/4885 |
| US-20050255081-A1 | Stabilizers for hydrolyzable organic binders | ALKBH2, PHOSPHO1, ALKBH1 | MAPT 1438/4885AKR1C3 3137/4885RXRA 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.