Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293184 | 0.85 | MAPT (0.49) | ALDH1A1AKR1C3HTTTDP1MAPT | |
| SCHEMBL3297649 | 0.83 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2AKR1C3LMNAHTT | |
| SCHEMBL6357912 | 0.75 | MAPT (0.41) | AKR1C3HTTHPGDMAPTCES2 | |
| P-Xylene SCHEMBL28217963 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2AKR1C3LMNAHTT | |
| SCHEMBL3791372 | 0.69 | MAPT (0.36) | ALDH1A1SMN1; SMN2AKR1C3LMNAHPGD | |
| SCHEMBL3787971 | 0.69 | MAPT (0.49) | ALDH1A1AKR1C3HTTHPGDTDP1 | |
| SCHEMBL9956060 | 0.68 | AKR1C3 (0.69) | ALDH1A1SMN1; SMN2AKR1C3HTTHPGD | |
| SCHEMBL474138 | 0.68 | AKR1C3 (0.69) | ALDH1A1SMN1; SMN2AKR1C3HTTHPGD | |
| SCHEMBL1920235 | 0.68 | AKR1C3 (0.69) | ALDH1A1SMN1; SMN2AKR1C3HTTHPGD | |
| SCHEMBL14423366 | 0.68 | MMP9 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100183540-A1 | BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER | JOTUN A/S (NO) | 2010-07-22 | — | — | US | disclosed |