Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752120 | 0.98 | LMNA (0.38) | LMNASMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL8752124 | 0.90 | LMNA (0.39) | LMNASMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL332722 | 0.88 | LMNA (0.42) | LMNASMN1; SMN2HPGDRECQLCA2 | |
| SCHEMBL8726308 | 0.85 | LMNA (0.41) | LMNASMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL371082 | 0.82 | LMNA (0.46) | LMNASMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL333577 | 0.81 | LMNA (0.45) | LMNASMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL9076702 | 0.80 | LMNA (0.44) | LMNASMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL332859 | 0.78 | LMNA (0.54) | LMNASMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL8752131 | 0.78 | LMNA (0.42) | LMNASMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL8995619 | 0.77 | LMNA (0.44) | LMNASMN1; SMN2TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050265923-A1 | Embolus therapy using insoluble microparticles or vesicles containing contrast agents | TONER JOHN L | 2005-12-01 | — | — | US | claimed |
| US-5525328-A | ADMINISTERING BEFORE X-RAY EXPOSURE | NANOSYSTEMS L.L.C. (US) | 1996-06-11 | — | — | US | claimed |
| US-5668196-A | 3-amido-triiodophenyl esters as x-ray contrast agents | NANOSYSTEMS LLC (US) | 1997-09-16 | — | — | US | disclosed |
| US-5643552-A | Nanoparticulate diagnostic mixed carbonic anhydrides as x-ray contrast agents for blood pool and lymphatic system imaging | NANOSYSTEMS L.L.C. (US) | 1997-07-01 | — | — | US | disclosed |
| WO-1997006132-A1 | TRIIODOALKYLPHENYL ESTERS AS NOVEL X-RAY CONTRAST AGENTS | NANOSYSTEMS L.L.C. (US) | 1997-02-20 | — | — | WO | disclosed |
| WO-1997005905-A1 | NOVEL 3-AMIDO-TRIIODOPHENYL ESTERS AS X-RAY CONTRAST AGENTS | NANOSYSTEMS L.L.C. (US) | 1997-02-20 | — | — | WO | disclosed |
| US-5573749-A | Nanoparticulate diagnostic mixed carboxylic anhydrides as X-ray contrast agents for blood pool and lymphatic system imaging | NANO SYSTEMS L.L.C. (US) | 1996-11-12 | — | — | US | disclosed |
| WO-1996028414-A1 | NANOPARTICULATE DIAGNOSTIC TRIIODO BENZOATE DERIVATIVES AS X-RAY CONTRAST AGENTS FOR BLOOD POOL AND LYMPHATIC SYSTEM IMAGING | NANOSYSTEMS L.L.C. (US) | 1996-09-19 | — | — | WO | disclosed |
| WO-1996024383-A1 | NANOPARTICULATE DIAGNOSTIC DIMERS AS X-RAY CONTRAST AGENTS FOR BLOOD POOL AND LYMPHATIC SYSTEM IMAGING | NANOSYSTEMS L.L.C. (US) | 1996-08-15 | — | — | WO | disclosed |
| US-5525328-A | ADMINISTERING BEFORE X-RAY EXPOSURE | NANOSYSTEMS L.L.C. (US) | 1996-06-11 | — | — | US | disclosed |
| US-5521218-A | Nanoparticulate iodipamide derivatives for use as x-ray contrast agents | NANOSYSTEMS L.L.C. (US) | 1996-05-28 | — | — | US | disclosed |
| US-5500204-A | Nanoparticulate diagnostic dimers as x-ray contrast agents for blood pool and lymphatic system imaging | EASTMAN KODAK COMPANY (US) | 1996-03-19 | — | — | US | disclosed |
| US-5472683-A | Nanoparticulate diagnostic mixed carbamic anhydrides as X-ray contrast agents for blood pool and lymphatic system imaging | EASTMAN KODAK COMPANY (US) | 1995-12-05 | — | — | US | disclosed |