SCHEMBL6358331

SCHEMBL6358331

C1=CCC(c2ccccc2)(P(c2ccccc2)c2ccccc2)C=C1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
HDAC4 P56524 1/20 0.30
CYP3A4 P08684 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28876299 0.78
SCHEMBL29009347 0.74
SCHEMBL2283117 0.70 HDAC4 (0.34) MAOAMAOBTAAR1HDAC4
SCHEMBL8039521 0.68 PNMT (0.39) MAOAMAOBTAAR1
SCHEMBL27449113 0.68 HDAC4 (0.33) MAOAMAOBTAAR1HDAC4
SCHEMBL3357684 0.67 HDAC4 (0.36) HDAC4
SCHEMBL16163009 0.67 HDAC4 (0.32) HDAC4
SCHEMBL5715764 0.67 MAOB (0.38) MAOAMAOBHDAC4
SCHEMBL276639 0.67 HDAC4 (0.32) HDAC4
SCHEMBL4089733 0.67 HDAC4 (0.36) MAOAMAOBHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050038289-A1 Chemical reactions in compressed carbon dioxide GORDON RICHARD S (GB) 2005-02-17 US claimed
EP-1409131-A2 PALLADIUM-CATALYSED CARBON-CARBON BOND FORMING REACTIONS IN COMPRESSED CARBON DIOXIDE Holmes, Andrew Bruce (GB) 2004-04-21 EP claimed
WO-2003009936-A2 PALLADIUM-CATALYSED CARBON-CARBON BOND FORMING REACTIONS IN COMPRESSED CARBON DIOXIDE HOLMES ANDREW BRUCE (GB) 2003-02-06 WO claimed
WO-2025087365-A1 METTL3 INHIBITOR 杭州邦顺制药有限公司 2025-05-01 WO disclosed
US-20050038289-A1 Chemical reactions in compressed carbon dioxide GORDON RICHARD S (GB) 2005-02-17 US disclosed
US-20050038289-A1 Chemical reactions in compressed carbon dioxide GORDON RICHARD S (GB) 2005-02-17 US disclosed
EP-1409131-A2 PALLADIUM-CATALYSED CARBON-CARBON BOND FORMING REACTIONS IN COMPRESSED CARBON DIOXIDE Holmes, Andrew Bruce (GB) 2004-04-21 EP disclosed
EP-1409131-A2 PALLADIUM-CATALYSED CARBON-CARBON BOND FORMING REACTIONS IN COMPRESSED CARBON DIOXIDE Holmes, Andrew Bruce (GB) 2004-04-21 EP disclosed
WO-2003009936-A3 PALLADIUM-CATALYSED CARBON-CARBON BOND FORMING REACTIONS IN COMPRESSED CARBON DIOXIDE HOLMES ANDREW BRUCE (GB) 2003-08-21 WO disclosed
WO-2003009936-A2 PALLADIUM-CATALYSED CARBON-CARBON BOND FORMING REACTIONS IN COMPRESSED CARBON DIOXIDE HOLMES ANDREW BRUCE (GB) 2003-02-06 WO disclosed
WO-2003009936-A2 PALLADIUM-CATALYSED CARBON-CARBON BOND FORMING REACTIONS IN COMPRESSED CARBON DIOXIDE HOLMES ANDREW BRUCE (GB) 2003-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038289-A1 Chemical reactions in compressed carbon dioxide TERT, TXK, CHKB MAOA 2016/4885MAOB 1390/4885TAAR1 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.