Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.34 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223566 | 0.91 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHTR1ASYK | |
| SCHEMBL224554 | 0.91 | LTA4H (0.50) | LTA4HMAPK14HTR1AABCB1DRD2 | |
| SCHEMBL226843 | 0.88 | NISCH (0.48) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL224611 | 0.88 | TP53 (0.45) | ALDH1A1MEN1KMT2ASYKRAB9A | |
| SCHEMBL224876 | 0.88 | MEN1 (0.44) | ALDH1A1MEN1KMT2ASYKMAPK1 | |
| SCHEMBL224997 | 0.88 | GAA (0.47) | ALDH1A1DRD2SMN1; SMN2LMNAAPP | |
| SCHEMBL223663 | 0.87 | RXRA (0.46) | ALDH1A1DRD2 | |
| SCHEMBL224978 | 0.87 | NISCH (0.51) | ALDH1A1MEN1KMT2AHTR1ASMN1; SMN2 | |
| SCHEMBL222619 | 0.85 | NISCH (0.50) | MEN1KMT2AHTR1AABCB1DRD2 | |
| SCHEMBL225470 | 0.85 | ADRA1D (0.55) | ALDH1A1MEN1KMT2ASYKRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317068-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY | 2021-10-14 | — | — | US | disclosed |
| US-11072576-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2021-07-27 | — | — | US | disclosed |
| US-20190345094-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY | 2019-11-14 | — | — | US | disclosed |
| US-10385005-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2019-08-20 | — | — | US | disclosed |
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2018-06-19 | — | — | US | disclosed |
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2018-06-19 | — | — | US | disclosed |
| US-20160137585-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY (US) | 2016-05-19 | — | — | US | disclosed |
| US-9181162-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-20120121536-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317068-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | ALDH1A1 2181/4885LTA4H 3747/4885MAPK14 1360/4885 |
| US-20160137585-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | ALDH1A1 2181/4885LTA4H 3747/4885MAPK14 1360/4885 |
| US-10385005-B2 | Compositions and methods for glucose transport inhibition | SLC2A1, SLC2A4, SLC2A3 | ALDH1A1 2181/4885LTA4H 3747/4885MAPK14 1360/4885 |
| US-20190345094-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | ALDH1A1 2181/4885LTA4H 3747/4885MAPK14 1360/4885 |
| US-11072576-B2 | Compositions and methods for glucose transport inhibition | SLC2A1, SLC2A4, SLC2A3 | ALDH1A1 2181/4885LTA4H 3747/4885MAPK14 1360/4885 |
| US-20120121536-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | ALDH1A1 2181/4885LTA4H 3747/4885MAPK14 1360/4885 |
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | SLC2A1, SLC2A4, SLC2A3 | ALDH1A1 2181/4885LTA4H 3747/4885MAPK14 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.