Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2369264 | 0.75 | ADORA1 (0.37) | ADORA1TMIGD3ADORA2A | |
| SCHEMBL2369044 | 0.67 | MCL1 (0.34) | ADORA1TMIGD3 | |
| SCHEMBL3384503 | 0.67 | MCL1 (0.36) | — | |
| SCHEMBL6364094 | 0.58 | LIMK1 (0.43) | — | |
| SCHEMBL512901 | 0.56 | ADORA1 (0.36) | ADORA1TMIGD3ADORA2A | |
| SCHEMBL2056343 | 0.55 | CYP1A2 (0.39) | ADORA1ADORA2A | |
| SCHEMBL2368440 | 0.54 | MCL1 (0.48) | — | |
| SCHEMBL2716516 | 0.54 | CYP11B1 (0.59) | ADORA1ADORA2A | |
| SCHEMBL1687466 | 0.53 | LPL (0.46) | ADORA1ADORA2A | |
| SCHEMBL26329041 | 0.53 | ADORA2A (0.48) | ADORA1TMIGD3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026935-A1 | Compounds | XENTION DISCOVERY LTD. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026935-A1 | Compounds | KCNJ11, KCNJ1, KCNH1 | ADORA1 528/4885TMIGD3 4357/4885ADORA2A 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.