Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL635965

CCCCOS(=O)(=O)[O-].N.[H+]

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.72
RECQL P46063 2/20 0.72
GLA P06280 1/20 0.72
HPGD P15428 1/20 0.72
MAPK1 P28482 1/20 0.72
EPHX2 P34913 1/20 0.72
BLM P54132 1/20 0.72
CA1 P00915 12/20 0.54
CA2 P00918 12/20 0.54
CA9 Q16790 9/20 0.46
CA12 O43570 4/20 0.45
CA7 P43166 4/20 0.45
CA14 Q9ULX7 3/20 0.45
CA3 P07451 2/20 0.45
CA4 P22748 2/20 0.45
CA6 P23280 2/20 0.45
CA5A P35218 2/20 0.45
CA5B Q9Y2D0 2/20 0.45
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2634750 0.98
Fluoride SCHEMBL28262916 0.93 TSHR (0.76) TSHRRECQLGLAHPGDMAPK1
Potassium Ion SCHEMBL6534824 0.93 TSHR (0.75) TSHRRECQLGLAHPGDMAPK1
SCHEMBL17456497 0.93 TSHR (0.75) TSHRRECQLGLAHPGDMAPK1
Lithium Ion SCHEMBL17456624 0.93 TSHR (0.75) TSHRRECQLGLAHPGDMAPK1
SCHEMBL302087 0.93 TSHR (0.83) TSHRRECQLGLAHPGDMAPK1
Zinc Ion SCHEMBL31471926 0.93 TSHR (0.75) TSHRRECQLGLAHPGDMAPK1
Amylosulfuric Acid SCHEMBL1531835 0.91 RECQL (0.87) TSHRRECQLGLAHPGDMAPK1
SCHEMBL11046781 0.88 RECQL (0.91) TSHRRECQLGLAHPGDMAPK1
SCHEMBL11372853 0.88 RECQL (0.91) TSHRRECQLGLAHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230072265-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF 4-({(1 R)-2-[5-(2-FLUORO-3METHOXYPHENYL)-3-{[2-FLUORO-6-(TRIFLUORO METHYL) PHENYL]METHYL}-4-METHYL-2,6-DIOXO-3,6DIHYDROPYRIMIDIN-1(2 H)-YL]-1-PHENYLETHYL}AMINO)BUTANOIC ACID OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2023-03-09 US claimed
WO-2022097115-A1 AN IMPROVED PROCESS FOR PREPARATION OF PROHEXADIONE AND ITS CALCIUM SALT HIKAL LIMITED (IN) 2022-05-12 WO claimed
WO-2021130776-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF 4-({(1 R)-2-[5-(2-FLUORO-3METHOXYPHENYL)-3-{[2-FLUORO-6-(TRIFLUORO METHYL) PHENYL]METHYL}-4-METHYL-2,6-DIOXO-3,6DIHYDROPYRIMIDIN-1(2 H)-YL]-1-PHENYLETHYL}AMINO)BUTANOIC ACID OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2021-07-01 WO claimed
WO-2021079380-A1 IMPROVED PROCESS FOR THE PREPARATION OF (2S)-N-{(1S)-1-(2-CHLOROPHENYL)-2-[(3,3-DIFLUOROCYCLOBUTYL)-AMINO]-2-OXOETHYL}-1-(4-CYANOPYRIDIN-2-YL)-N-(5-FLUOROPYRIDIN-3-YL)-5-OXOPYRROLIDINE-2-CARBOXAMIDE MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2021-04-29 WO claimed
WO-2020044102-A1 BROMINE FREE PREPARATION OF 5H-DIBENZO [A,D] CYCLOHEPTEN-5-ONE R L FINE CHEM PRIVATE LIMITED (IN) 2020-03-05 WO claimed
CN-110467567-A A kind of preparation method of ZEN 90160 CAC NANTONG CHEMICAL CO LTD 2019-11-19 CN claimed
CN-109369708-A A kind of green synthesis process of O, O- diethyl sulfo-phosphoryl chloride 重庆华歌生物化学有限公司 2019-02-22 CN claimed
CN-105585525-B A kind of synthetic method of Montelukast Sodium 山东新时代药业有限公司 2018-08-14 CN claimed
CN-104803969-B A kind of acrylic type contains thio sulfonate group high refractive index monomers and its synthetic method 合肥工业大学 2017-12-19 CN claimed
US-20170291866-A1 Production of Mixed Aldol Products from the Products of Hydroformylation Reactions Texmark Chemicals, Inc. (US) 2017-10-12 US claimed
WO-2008126106-A2 NOVEL AND IMPROVED PROCESSES FOR THE PREPARATION OF INTERMEDIATES OF DARIFENACIN, DARIFENACIN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS SATYANARAYANA REDDY MANNE (IN) 2008-10-23 WO claimed
WO-2007148344-A2 PROCESS FOR THE PREPARATION OF OLMESARTAN MEDOXOMIL MATRIX LABORATORIES LIMITED (IN) 2007-12-27 WO claimed
EP-1704134-B1 A PROCESS FOR ISOLATING, PURIFYING AND FORMULATING A STABLE, COMMERCIAL GRADE LUTEIN PASTE FROM OLEORESIN INDUS BIOTECH PVT LTD (IN) 2007-11-07 EP claimed
WO-2007122638-A2 AN IMPROVED PROCESS FOR PREPARATION OF LAMOTRIGINE INTERMEDIATES RATNAMANI BIO-CHEMICALS & PHARMACEUTICALS PVT. LTD. (IN) 2007-11-01 WO claimed
US-7179930-B2 Process for isolating, purifying and formulating a stable, commercial grade Lutein paste from oleoresin INDUS BIOTECH PRIVATE LIMITED (IN) 2007-02-20 US claimed
US-20060252940-A1 CRYSTALLINE 1-[2-(2,4-DIFLUOROPHENYL)-OXIRANYL METHYL]-1H-1,2,4-TRIAZOLE DR. REDDY'S LABORATORIES, INC. 2006-11-09 US claimed
EP-1704134-A1 A PROCESS FOR ISOLATING, PURIFYING AND FORMULATING A STABLE, COMMERCIAL GRADE LUTEIN PASTE FROM OLEORESIN Indus Biotech Pvt. Ltd. (IN) 2006-09-27 EP claimed
WO-2006035459-A1 AN IMPROVED PROCESS FOR THE PRODUCTION OF DERIVATIVES OF THIOZOLIDINEDIONES AND THEIR PRECURSORS MOREPEN LABORATORIES LIMITED (IN) 2006-04-06 WO claimed
US-20050182280-A1 Process for isolating, purifying and formulating a stable, commercial grade Lutein paste from oleoresin INDUS BIOTECH PVT. LTD. (IN) 2005-08-18 US claimed
WO-2005068409-A1 A PROCESS FOR ISOLATING, PURIFYING AND FORMULATING A STABLE, COMMERCIAL GRADE LUTEIN PASTE FROM OLEORESIN INDUS BIOTECH PRIVATE LIMITED (IN) 2005-07-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252940-A1 CRYSTALLINE 1-[2-(2,4-DIFLUOROPHENYL)-OXIRANYL METHYL]-1H-1,2,4-TRIAZOLE CYP2F1, CYP4B1, CYP3A4 TSHR 3316/4885RECQL 1564/4885GLA 1716/4885
US-20050182280-A1 Process for isolating, purifying and formulating a stable, commercial grade Lutein paste from oleoresin LRAT, LIPC, LIPA TSHR 2123/4885RECQL 419/4885GLA 871/4885
US-20230072265-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF 4-({(1 R)-2-[5-(2-FLUORO-3METHOXYPHENYL)-3-{[2-FLUORO-6-(TRIFLUORO METHYL) PHENYL]METHYL}-4-METHYL-2,6-DIOXO-3,6DIHYDROPYRIMIDIN-1(2 H)-YL]-1-PHENYLETHYL}AMINO)BUTANOIC ACID OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS BPNT1, GABRA6, GABRA1 TSHR 3072/4885RECQL 4402/4885GLA 3864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.