SCHEMBL6359929

SCHEMBL6359929

O=S(=O)(O)c1cc(F)ccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.49
HPGD P15428 2/20 0.49
LMNA P02545 1/20 0.49
HIF1A Q16665 1/20 0.49
CA3 P07451 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
EGFR P00533 1/20 0.42
ALDH1A1 P00352 2/20 0.39
PTGS1 P23219 1/20 0.39
ACLY P53396 1/20 0.39
NQO1 P15559 1/20 0.38
MEN1 O00255 1/20 0.37
HPGDS O60760 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
COMT P21964 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13018722 0.83 CA9 (0.48) HSD17B10HPGDLMNAHIF1ACA3
SCHEMBL10838459 0.83 CA9 (0.46) CA3CA6CA5ACA9CA14
SCHEMBL10590409 0.82 PARP1 (0.41) CA3CA6CA5ACA9CA14
SCHEMBL22396701 0.81 CA3 (0.41) CA3CA6CA5ACA9CA14
SCHEMBL3195282 0.80 PKM (0.47) CA3CA6CA5ACA9CA14
SCHEMBL31385189 0.79 PTGS1 (0.60) CA3CA6CA5ACA9CA14
Hydrochloric Acid SCHEMBL28046977 0.78 PKM (0.46) CA3CA6CA5ACA9CA14
SCHEMBL3935279 0.78 PKM (0.46) CA3CA6CA5ACA9CA14
Dobesilic Acid SCHEMBL232087 0.77 LMNA (0.72) HSD17B10HPGDLMNAHIF1ACA9
SCHEMBL1535883 0.77 HSD17B10 (0.52) HSD17B10HPGDLMNAHIF1AEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6441216-B1 CHEMICAL INTERMEDIATES; ELECTROLYTES MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2002-08-27 US claimed
CN-115901713-A Circulating tumor cell detection method 中国科学院宁波材料技术与工程研究所 2023-04-04 CN disclosed
CN-114736156-A Preparation method and application of simplified derivatives of cryptolepine 中捷四方生物科技股份有限公司 2022-07-12 CN disclosed
US-6864017-B2 Method of preparing lithium complex salts for use in electrochemical cells MERCK PATENT GMBH (DE) 2005-03-08 US disclosed
CN-1177849-C Method for preparing lithium matched salt for electrochemical cell Ĭ��ר���ɷ����޹�˾ 2004-12-01 CN disclosed
EP-1069128-B1 Process for preparing complex lithium salts for use in electrochemical cells MERCK PATENT GMBH (DE) 2004-11-10 EP disclosed
US-20040091785-A1 Method of preparing lithium complex salts for use in electrochemical cells LEONOV ANDREI (DE) 2004-05-13 US disclosed
US-6657072-B2 O-sulfo-phenol where one or both of the groups is protected by a trialkylsilyl group, by reacting the phenol with chlorosulfonic acid and then with chlorotrimethylsilane; lithium bis(2-olato-benzenesulfonato(2)-O,O')borate(1-) MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 2003-12-02 US disclosed
US-20030028023-A1 Method of preparing lithium complex salts for use in electrochemical cells LEONOV ANDREI (DE) 2003-02-06 US disclosed
US-6441216-B1 CHEMICAL INTERMEDIATES; ELECTROLYTES MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2002-08-27 US disclosed
EP-1069128-A2 Process for preparing complex lithium salts for use in electrochemical cells MERCK PATENT GmbH (DE) 2001-01-17 EP disclosed
CN-1280130-A Method for preparing lithium matched salt for electrochemical cell MERCK PATENT GMBH (DE) 2001-01-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030028023-A1 Method of preparing lithium complex salts for use in electrochemical cells CA3, MCU, CACNA2D3 HSD17B10 2371/4885HPGD 2480/4885LMNA 58/4885
US-20040091785-A1 Method of preparing lithium complex salts for use in electrochemical cells CA3, MCU, CACNA2D3 HSD17B10 2371/4885HPGD 2480/4885LMNA 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.