Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6362941 | 0.81 | MAPT (0.38) | SQORDAPK3PRKD3MAP4K4ABL1 | |
| SCHEMBL2368787 | 0.77 | CYP1A2 (0.42) | SQORESR1DAPK3PRKD3MAP4K4 | |
| SCHEMBL6359338 | 0.76 | ESR1 (0.38) | ESR1DAPK3PRKD3MAP4K4ABL1 | |
| SCHEMBL6364382 | 0.74 | ESR1 (0.45) | ESR1DAPK3PRKD3MAP4K4ABL1 | |
| SCHEMBL6359795 | 0.73 | ALDH1A1 (0.42) | ESR1DAPK3PRKD3MAP4K4ABL1 | |
| SCHEMBL5790639 | 0.71 | HTT (0.35) | DAPK3PRKD3MAP4K4ABL1NTRK1 | |
| SCHEMBL2368948 | 0.70 | ALDH1A1 (0.38) | DAPK3PRKD3MAP4K4ABL1NTRK1 | |
| SCHEMBL5789324 | 0.70 | FGFR1 (0.35) | ESR1DAPK3PRKD3MAP4K4ABL1 | |
| SCHEMBL6364115 | 0.69 | HTT (0.41) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL2368759 | 0.69 | BTK (0.39) | ESR1DAPK3PRKD3MAP4K4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026935-A1 | Compounds | XENTION DISCOVERY LTD. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026935-A1 | Compounds | KCNJ11, KCNJ1, KCNH1 | SQOR 174/4885ESR1 4494/4885DAPK3 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.