Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690445 | 0.94 | TSHR (0.50) | — | |
| SCHEMBL10526715 | 0.94 | — | — | |
| Tetramethylammonium Ion SCHEMBL10643396 | 0.88 | TSHR (0.46) | — | |
| SCHEMBL6726187 | 0.86 | TSHR (0.43) | — | |
| Bicarbonate SCHEMBL3706559 | 0.77 | TSHR (0.78) | — | |
| SCHEMBL5704223 | 0.71 | — | — | |
| SCHEMBL36670 | 0.69 | TSHR (0.59) | — | |
| SCHEMBL297916 | 0.69 | TSHR (0.59) | — | |
| Isopropyl Fumarate SCHEMBL30863913 | 0.69 | HCAR2 (0.61) | — | |
| Potassium Ion SCHEMBL9186236 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104672210-B | The preparation method of Egelieting and alogliptin benzoate | 北大方正集团有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-105153026-B | Sorafenib derivative of the amide structure containing biaryl and its preparation method and application | 江西科技师范大学 | 2018-02-02 | — | — | CN | disclosed |
| US-20050044778-A1 | Fuel compositions employing catalyst combustion structure | OCTANE INTERNATIONAL, LTD. | 2005-03-03 | — | — | US | disclosed |
| EP-1051461-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR, William C. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999066009-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR WILLIAM C (US) | 1999-12-23 | — | — | WO | disclosed |