Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.74 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1159948 | 0.84 | BACE1 (0.61) | NR1H4MAOBBACE1CYP1A1CYP1B1 | |
| SCHEMBL5138170 | 0.82 | MAOB (0.82) | NR1H4MAOBARMAPTACHE | |
| SCHEMBL5138171 | 0.82 | MAOB (0.82) | NR1H4MAOBARMAPTACHE | |
| SCHEMBL30237661 | 0.82 | NR1H4 (0.67) | NR1H4MAOBARABCG2CYP1A1 | |
| SCHEMBL636137 | 0.81 | BACE1 (0.74) | NR1H4MAOBARBACE1MAPT | |
| SCHEMBL20608557 | 0.79 | MAPT (0.68) | NR1H4MAOBMAPTABCG2MEN1 | |
| SCHEMBL5313681 | 0.77 | NR1H4 (0.64) | NR1H4MAOBARBACE1MAPT | |
| SCHEMBL21317661 | 0.76 | PKM (0.56) | BACE1MAPTABCG2MEN1MAPK1 | |
| SCHEMBL11776410 | 0.76 | MAPT (0.66) | NR1H4ARMAPTNPC1MAPK1 | |
| SCHEMBL26046382 | 0.76 | KDM4E (0.60) | BACE1MAPTABCG2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12257280-B2 | Composition for preventing or treating muscular diseases, containing, as active ingredient, Glycyrrhiza uralensis extract or compound isolated therefrom | NEO CREMAR CO., LTD. (KR) | 2025-03-25 | — | — | US | disclosed |
| CN-115919924-A | Composition for preventing or treating muscular disease comprising licorice extract or compound isolated therefrom as active ingredient | 新可利玛股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112739362-B | Composition for preventing or treating muscular disease comprising licorice extract or compound isolated therefrom as active ingredient | 新可利玛股份有限公司 | 2022-08-23 | — | — | CN | disclosed |
| US-20210315957-A1 | COMPOSITION FOR PREVENTING OR TREATING MUSCULAR DISEASES, CONTAINING, AS ACTIVE INGREDIENT, GLYCYRRHIZA URALENSIS EXTRACT OR COMPOUND ISOLATED THEREFROM | RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY (KR) | 2021-10-14 | — | — | US | disclosed |
| CN-112739362-A | Composition for preventing or treating muscular disease comprising licorice extract or compound isolated therefrom as active ingredient | 岭南大学校产学协力团 | 2021-04-30 | — | — | CN | disclosed |
| EP-3811959-A1 | COMPOSITION FOR PREVENTING OR TREATING MUSCULAR DISEASES, CONTAINING, AS ACTIVE INGREDIENT, GLYCYRRHIZA URALENSIS EXTRACT OR COMPOUND ISOLATED THEREFROM | Research Cooperation Foundation of Yeungnam University (KR) | 2021-04-28 | — | — | EP | disclosed |
| WO-2020256397-A1 | COMPOSITION FOR PREVENTING OR TREATING MUSCULAR DISEASES, CONTAINING, AS ACTIVE INGREDIENT, GLYCYRRHIZA URALENSIS EXTRACT OR COMPOUND ISOLATED THEREFROM | 영남대학교 산학협력단 | 2020-12-24 | — | — | WO | disclosed |
| JP-2001253823-A | HIV GENE EXPRESSION INHIBITOR | TANUMA YASUKAZU | 2001-09-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315957-A1 | COMPOSITION FOR PREVENTING OR TREATING MUSCULAR DISEASES, CONTAINING, AS ACTIVE INGREDIENT, GLYCYRRHIZA URALENSIS EXTRACT OR COMPOUND ISOLATED THEREFROM | PYGM, MUSK, GYS1 | NR1H4 1550/4885MAOB 4266/4885AR 2499/4885 |
| US-12257280-B2 | Composition for preventing or treating muscular diseases, containing, as active ingredient, Glycyrrhiza uralensis extract or compound isolated therefrom | PYGM, MUSK, GYS1 | NR1H4 1550/4885MAOB 4266/4885AR 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.