Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | GPR6 | P46095 | 8/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6104086 | 0.79 | PTGDR (0.45) | PTGDRIKBKBHRH1CCR3GPR6 | |
| SCHEMBL6362089 | 0.78 | PTGDR (0.41) | PTGDRIKBKBGPR6SMN1; SMN2 | |
| SCHEMBL6218902 | 0.76 | PTGDR (0.42) | PTGDRIKBKBGPR6RORC | |
| SCHEMBL6218839 | 0.76 | PTGDR (0.42) | PTGDRIKBKBGPR6SMN1; SMN2RORC | |
| SCHEMBL6245802 | 0.75 | PTGDR (0.44) | PTGDRIKBKBHRH1CCR3SCD | |
| SCHEMBL6245804 | 0.75 | PTGDR (0.44) | PTGDRIKBKBHRH1CCR3SCD | |
| SCHEMBL6104724 | 0.75 | PTGDR (0.44) | PTGDRIKBKBHRH1CCR3SCD | |
| SCHEMBL6103913 | 0.74 | TDO2 (0.47) | IKBKBGPR6RORC | |
| SCHEMBL6246834 | 0.74 | IKBKB (0.42) | PTGDRIKBKBHRH1CCR3SCD | |
| SCHEMBL6246832 | 0.73 | IKBKB (0.43) | PTGDRIKBKBGPR6MMP13SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539159-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | Astrazeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004006926-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |