SCHEMBL6364153

C[Si](C)(C)C#Cc1cc(C#C[Si](C)(C)C)cc(Oc2ccc(C34CC5CC(C3)CC(c3ccc(Oc6cc(C#C[Si](C)(C)C)cc(C#C[Si](C)(C)C)c6)cc3)(C5)C4)cc2)c1

nearest known ligand 0.45

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	ESR1	P03372	1/20	0.45

▸	PGR	P06401	10/20	0.43

▸	ALDH1A1	P00352	4/20	0.37

▸	LMNA	P02545	4/20	0.36

▸	MEN1	O00255	2/20	0.36

▸	KMT2A	Q03164	2/20	0.36

▸	L3MBTL1	Q9Y468	1/20	0.36

▸	RAB9A	P51151	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	HSD11B1	P28845	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5847067	0.83	PGR (0.42)	ESR1PGRALDH1A1LMNAMEN1
SCHEMBL6369358	0.81	PGR (0.48)	ESR1PGRALDH1A1LMNAMEN1
SCHEMBL4064832	0.77	PGR (0.37)	ESR1PGRALDH1A1LMNA
SCHEMBL4052728	0.74	PGR (0.35)	ESR1PGRALDH1A1LMNA
SCHEMBL6767202	0.74	LMNA (0.41)	PGRALDH1A1LMNAMEN1KMT2A
SCHEMBL2710493	0.74	ALDH1A1 (0.64)	ESR1PGRALDH1A1LMNAMEN1
SCHEMBL6364219	0.73	MEN1 (0.47)	ESR1PGRALDH1A1LMNAMEN1
SCHEMBL18084692	0.70	PGR (0.33)	PGR
SCHEMBL4063964	0.70	—	—
SCHEMBL6764265	0.69	HTT (0.38)	ALDH1A1LMNAMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20050025892-A1	Composition for porous organic film	SUMITOMO CHEMICAL COMPANY, LIMITED	2005-02-03	—	—	US	disclosed