Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052728 | 0.97 | PGR (0.35) | PGRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5847067 | 0.93 | PGR (0.42) | PGRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4063964 | 0.87 | — | — | |
| SCHEMBL6767202 | 0.86 | LMNA (0.41) | PGRALDH1A1LMNA | |
| SCHEMBL2188872 | 0.84 | PGR (0.42) | PGRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2189181 | 0.83 | PGR (0.43) | PGRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2188045 | 0.79 | PGR (0.42) | PGRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2189497 | 0.78 | GRIN2D (0.45) | PGRALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6764265 | 0.78 | HTT (0.38) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2188546 | 0.78 | GRIN2D (0.42) | PGRALDH1A1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090030248-A1 | Ethynylphenylbiadamantane derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-2014636-A1 | Ethynylphenylbiadamantane derivatives | Daicel Chemical Industries, Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030248-A1 | Ethynylphenylbiadamantane derivatives | CHRNA5, CHRNE, ADRA1D | PGR 1708/4885ALDH1A1 1329/4885GRIN2D 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.