Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522633 | 0.87 | MAPT (0.64) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL3165396 | 0.87 | CHEK2 (0.57) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL29812691 | 0.87 | CHEK2 (0.57) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL12117371 | 0.84 | CHEK2 (0.55) | CHEK2ROS1MARK3LTKFLT4 | |
| SCHEMBL666531 | 0.83 | MAPT (0.62) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL29724705 | 0.80 | RAB9A (0.76) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL29569917 | 0.80 | METAP1 (0.52) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL28360994 | 0.80 | METAP1 (0.52) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL3129344 | 0.80 | METAP1 (0.52) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL65503 | 0.80 | RAB9A (0.76) | MAPTALDH1A1KDM4ELMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020115076-A2 | INSECT CONTROL AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2020-06-11 | — | — | WO | disclosed |
| US-6846953-B1 | Aromatic amides | WARNER LAMBERT COMPANY (US) | 2005-01-25 | — | — | US | disclosed |