SCHEMBL666531

SCHEMBL666531

Nc1ccc2c(c1)Cc1cc(Br)ccc1-2

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.62
LMNA P02545 3/20 0.62
ALDH1A1 P00352 3/20 0.62
RAB9A P51151 2/20 0.62
KDM4E B2RXH2 2/20 0.62
NPC1 O15118 1/20 0.62
HPGD P15428 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
TLR9 Q9NR96 1/20 0.51
METAP1 P53582 1/20 0.47
TDP2 O95551 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123584 0.87 RAB9A (0.78) MAPTLMNAALDH1A1RAB9AKDM4E
SCHEMBL29372630 0.87 RAB9A (0.78) MAPTLMNAALDH1A1RAB9AKDM4E
SCHEMBL29376113 0.87 METAP1 (0.57) MAPTLMNAALDH1A1RAB9AKDM4E
SCHEMBL40823 0.87 METAP1 (0.57) MAPTLMNAALDH1A1RAB9AKDM4E
SCHEMBL28126153 0.87 METAP1 (0.57) MAPTLMNAALDH1A1RAB9AKDM4E
Ammonia Solution, Strong SCHEMBL28144371 0.84 METAP1 (0.55) MAPTLMNAALDH1A1RAB9AKDM4E
SCHEMBL27619851 0.84 METAP1 (0.55) MAPTLMNAALDH1A1RAB9AKDM4E
Hydrochloric Acid SCHEMBL867181 0.84 RAB9A (0.75) MAPTLMNAALDH1A1RAB9AKDM4E
Hydrochloric Acid SCHEMBL17417855 0.84 RAB9A (0.75) MAPTLMNAALDH1A1RAB9AKDM4E
Hydrochloric Acid SCHEMBL30705049 0.84 RAB9A (0.75) MAPTLMNAALDH1A1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105037167-B A kind of synthetic method of N, N diaryl 2 bromine 6 naphthylamines and its application 华南理工大学 2017-03-01 CN claimed
CN-105037167-A Synthetic method of N, N-diaryl-2-bromine-6-naphthylamine and application thereof UNIV SOUTH CHINA TECH 2015-11-11 CN claimed
CN-104762477-A Method for recovering and treating waste containing silver component CHEN YIWEN 2015-07-08 CN claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
WO-1993014062-A1 ANTHELMINTIC β-KETOAMIDES THE UPJOHN COMPANY (US) 1993-07-22 WO claimed
EP-4440312-A1 INSECT NEUROPEPTIDE ANALOGUES Solasta Bio Limited (GB) 2024-10-09 EP disclosed
US-11806335-B2 Heterocyclic carboxylate compounds as glycolate oxidase inhibitors Lilac Therapeutics, Inc. (US) 2023-11-07 US disclosed
US-11806335-B2 Heterocyclic carboxylate compounds as glycolate oxidase inhibitors Lilac Therapeutics, Inc. (US) 2023-11-07 US disclosed
WO-2023099922-A1 INSECT NEUROPEPTIDE ANALOGUES Solasta Bio Limited (GB) 2023-06-08 WO disclosed
WO-2023099922-A1 INSECT NEUROPEPTIDE ANALOGUES Solasta Bio Limited (GB) 2023-06-08 WO disclosed
CN-105973472-B A kind of near-infrared fluorescent temperature sensing method and material 北京大学 2019-02-22 CN disclosed
CN-105037167-B A kind of synthetic method of N, N diaryl 2 bromine 6 naphthylamines and its application 华南理工大学 2017-03-01 CN disclosed
US-5670564-A Macromonomers having reactive end groups MAXDEM INCORPORATED (US) 1997-09-23 US disclosed
EP-0793643-A1 MATRIX METALLOPROTEASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1997-09-10 EP disclosed
EP-0599886-A4 MACROMONOMERS HAVING REACTIVE END GROUPS. MAXDEM INC (US) 1996-07-24 EP disclosed
WO-1996016027-A1 MATRIX METALLOPROTEASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1996-05-30 WO disclosed
EP-0599886-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1994-06-08 EP disclosed
US-5230998-A Viricides AIDA DEVELOPMENT CORPORATION 1993-07-27 US disclosed
WO-1993014062-A1 ANTHELMINTIC β-KETOAMIDES THE UPJOHN COMPANY (US) 1993-07-22 WO disclosed
WO-1993004099-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1993-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11806335-B2 Heterocyclic carboxylate compounds as glycolate oxidase inhibitors UGDH, PGD, PNPO MAPT 3488/4885LMNA 4767/4885ALDH1A1 184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.