Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 10/20 | 0.63 |
| ▸ | RARB | P10826 | 9/20 | 0.63 |
| ▸ | RARG | P13631 | 9/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.62 |
| ▸ | GOT1 | P17174 | 1/20 | 0.62 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13330402 | 0.88 | RARA (0.49) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL9622397 | 0.88 | RARA (0.53) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL9622366 | 0.87 | RARB (0.59) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL1082340 | 0.85 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL565789 | 0.85 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9124255 | 0.84 | RARA (0.76) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL14027627 | 0.83 | RARB (0.82) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL6364425 | 0.83 | RARA (0.71) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8616987 | 0.81 | RARA (0.65) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL9622379 | 0.81 | RARB (0.50) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050208001-A1 | PPAR receptor activator compounds for treating cutaneous disorders/afflictions | SOCIETE L'OREAL, S.A. (FR) | 2005-09-22 | — | — | US | disclosed |
| US-20030013734-A1 | PPAR receptor activator compounds for treating cutaneous disorders/afflictions | MAIGNAN JEAN (FR) | 2003-01-16 | — | — | US | disclosed |
| US-20020049250-A1 | PPAR receptor activator compounds for treating cutaneous disorders/afflictions | SOCIETE L'OREAL, S.A. (FR) | 2002-04-25 | — | — | US | disclosed |
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049250-A1 | PPAR receptor activator compounds for treating cutaneous disorders/afflictions | PPARG, PPARA, PPARD | RARA 12/4885RARB 20/4885RARG 28/4885 |
| US-20030013734-A1 | PPAR receptor activator compounds for treating cutaneous disorders/afflictions | PPARG, PPARA, PPARD | RARA 12/4885RARB 20/4885RARG 28/4885 |
| US-20050208001-A1 | PPAR receptor activator compounds for treating cutaneous disorders/afflictions | PPARG, PPARA, PPARD | RARA 12/4885RARB 23/4885RARG 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.