Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.53 |
| ▸ | RARB | P10826 | 4/20 | 0.53 |
| ▸ | RARG | P13631 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | GOT1 | P17174 | 1/20 | 0.53 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364992 | 0.88 | RARA (0.63) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL13330402 | 0.83 | RARA (0.49) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL5084769 | 0.79 | RARA (0.57) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9320668 | 0.79 | RARA (0.55) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9622366 | 0.77 | RARB (0.59) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL1082340 | 0.77 | RARA (0.77) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL565789 | 0.77 | RARA (0.77) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL9191306 | 0.76 | RARA (0.55) | RARARARBRARGKMT2AMEN1 | |
| SCHEMBL6535745 | 0.76 | RARA (0.47) | RARARARBRARGKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9124255 | 0.76 | RARA (0.76) | RARARARBRARGKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |