Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.66 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.64 |
| ▸ | BACE1 | P56817 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | CDK8 | P49336 | 2/20 | 0.54 |
| ▸ | CDK9 | P50750 | 2/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.54 |
| ▸ | GABRD | O14764 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365437 | 0.89 | ACHE (0.80) | APPACHEPLK1BACE1ALDH1A1 | |
| SCHEMBL4506253 | 0.84 | APP (0.69) | APPACHEPLK1BACE1ALDH1A1 | |
| SCHEMBL29358951 | 0.83 | APP (0.93) | APPACHEPLK1BACE1ALDH1A1 | |
| SCHEMBL6359647 | 0.80 | ACHE (0.81) | APPACHEPLK1BACE1PPARG | |
| SCHEMBL29100197 | 0.79 | APP (0.93) | APPACHEPLK1BACE1ALDH1A1 | |
| SCHEMBL30619516 | 0.79 | APP (0.93) | APPACHEPLK1BACE1ALDH1A1 | |
| Moslosooflavone SCHEMBL6070206 | 0.78 | ACHE (1.00) | APPACHEPLK1BACE1ALDH1A1 | |
| Moslosooflavone SCHEMBL29822243 | 0.78 | ACHE (1.00) | APPACHEPLK1BACE1ALDH1A1 | |
| SCHEMBL31238014 | 0.78 | ALDH1A1 (0.73) | APPACHEPLK1BACE1ALDH1A1 | |
| SCHEMBL987020 | 0.78 | ALDH1A1 (0.73) | APPACHEPLK1BACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909919-B1 | FLAVONOID IN THE FORM OF A SYNERGIST FOR ENHANCING A SELF-BROWNING SUBSTANCE EFFECT | MERCK PATENT GMBH (DE) | 2014-07-23 | — | — | EP | disclosed |
| EP-2004136-B1 | Use of flavonoids | MERCK PATENT GMBH (DE) | 2014-04-30 | — | — | EP | disclosed |
| US-8613910-B2 | Flavonoids as synergists for enhancing the action of self-tanning substances | MERCK PATENT GMBH (DE) | 2013-12-24 | — | — | US | disclosed |
| EP-1860158-B1 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GMBH (DE) | 2013-12-04 | — | — | EP | disclosed |
| US-7914893-B2 | Particles comprising an anion-binding layer containing anion-forming organic active compounds, and method of making and using thereof | MERCK PATENT GMBH (DE) | 2011-03-29 | — | — | US | disclosed |
| US-20090317342-A1 | USE OF FLAVONOIDS | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-24 | — | — | US | disclosed |
| US-7588783-B2 | 5-Hydroxy-7-methoxy-2-(4'-methoxyphenyl)-4-oxo-4H-chromen-8-yl]sulfonic acid; plant extracts; use in cosmetic for protecting skin, a pharmaceutical drug, food, or food supplement | MERCK PATENT GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-7588783-B2 | 5-Hydroxy-7-methoxy-2-(4'-methoxyphenyl)-4-oxo-4H-chromen-8-yl]sulfonic acid; plant extracts; use in cosmetic for protecting skin, a pharmaceutical drug, food, or food supplement | MERCK PATENT GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-20080279793-A1 | Flavonoids as Synergists for Enhancing the Action of Self-Tanning Substances | MERCK PATENT GMBH (DE) | 2008-11-13 | — | — | US | disclosed |
| EP-1689734-B1 | FLAVONOID DERIVATIVE | MERCK PATENT GMBH (DE) | 2008-07-23 | — | — | EP | disclosed |
| US-20070275244-A1 | Particles | MERCK PATENT GMBH | 2007-11-29 | — | — | US | disclosed |
| EP-1860158-A2 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-20070134172-A1 | 5-Hydroxy-7-methoxy-2-(4'-methoxyphenyl)-4-oxo-4H-chromen-8-yl]sulfonic acid; plant extracts; use in cosmetic for protecting skin, a pharmaceutical drug, food, or food supplement | EUROPEAN BRAND PARTICIPATIONS SA (LU) | 2007-06-14 | — | — | US | disclosed |
| US-20070134172-A1 | 5-Hydroxy-7-methoxy-2-(4'-methoxyphenyl)-4-oxo-4H-chromen-8-yl]sulfonic acid; plant extracts; use in cosmetic for protecting skin, a pharmaceutical drug, food, or food supplement | EUROPEAN BRAND PARTICIPATIONS SA (LU) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070134172-A1 | 5-Hydroxy-7-methoxy-2-(4'-methoxyphenyl)-4-oxo-4H-chromen-8-yl]sulfonic acid; plant extracts; use in cosmetic for protecting skin, a pharmaceutical drug, food, or food supplement | CYP8B1, TYR, CUTA | APP 4563/4885ACHE 1569/4885PLK1 2760/4885 |
| US-20090317342-A1 | USE OF FLAVONOIDS | OR51E2, TAS2R20, TAS2R60 | APP 1948/4885ACHE 123/4885PLK1 4295/4885 |
| US-20080279793-A1 | Flavonoids as Synergists for Enhancing the Action of Self-Tanning Substances | TEAD3, TPI1, TEAD2 | APP 2801/4885ACHE 122/4885PLK1 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.