Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.68 |
| ▸ | TUBB | P07437 | 1/20 | 0.68 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.68 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.68 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.68 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.68 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.68 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.68 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.68 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.68 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.68 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.68 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238014 | 1.00 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL14303808 | 0.90 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL6365437 | 0.88 | ACHE (0.80) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL28011841 | 0.88 | ACHE (0.79) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL30235468 | 0.86 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL29419950 | 0.86 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL987761 | 0.86 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL21981343 | 0.86 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL16894618 | 0.86 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AABCB1CYP3A4 | |
| SCHEMBL6926027 | 0.85 | ABCB1 (0.64) | ALDH1A1MEN1KMT2AABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114984103-B | Orange peel extract and preparation method and application thereof | 赣南师范大学 | 2023-10-03 | — | — | CN | claimed |
| CN-115969838-A | Application of natural composition as estrogen receptor degradation agent | 三峡大学 | 2023-04-18 | — | — | CN | claimed |
| CN-114558061-B | Loquat leaf extract and preparation method and application thereof | 浙江大学 | 2023-04-04 | — | — | CN | claimed |
| CN-115886131-A | Feed additive prepared from citrus leaf extract and preparation method thereof | 成都农业科技职业学院 | 2023-04-04 | — | — | CN | claimed |
| CN-114984103-A | Orange peel extract and preparation method and application thereof | 赣南师范大学 | 2022-09-02 | — | — | CN | claimed |
| CN-114558061-A | Loquat leaf extract and preparation method and application thereof | 浙江大学 | 2022-05-31 | — | — | CN | claimed |
| CN-113801084-A | Polymethoxyflavone extracted from orange vinegar fermentation substrate sludge, and extraction method and application thereof | 三峡大学 | 2021-12-17 | — | — | CN | claimed |
| CN-109374762-B | Method for identifying citrus reticulata blanco and citrus reticulata blanco varieties based on metabonomics | 广州中医药大学第一附属医院 | 2021-10-08 | — | — | CN | claimed |
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | claimed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | claimed |
| WO-2006132879-A2 | SOFT GEL CAPSULES CONTAINING POLYMETHOXYLATED FLAVONES AND PALM OIL TOCOTRIENOLS | SOFT GEL TECHNOLOGIES, INC. (US) | 2006-12-14 | — | — | WO | claimed |
| WO-2006127996-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2006-11-30 | — | — | WO | claimed |
| US-6987125-B1 | Compositions and methods of treating, reducing and preventing cardiovascular diseases and disorders with polymethoxyflavones | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2006-01-17 | — | — | US | claimed |
| US-20060003947-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | THE CIT GROUP/CREDIT FINANCE, INC. | 2006-01-05 | — | — | US | claimed |
| US-20050249803-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | SOFT GEL TECHNOLOGIES, INC. | 2005-11-10 | — | — | US | claimed |
| EP-1278417-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK Synergie (CA) | 2003-01-29 | — | — | EP | claimed |
| WO-2001070029-A1 | COMPOSITIONS AND METHODS OF TREATING, REDUCING, AND PREVENTING CARDIOVASCULAR DISEASES AND DISORDERS WITH POLYMETHOXYFLAVONES | KGK SYNERGIE (CA) | 2001-09-27 | — | — | WO | claimed |
| EP-0605261-B1 | Use of a flavone derivative as taste modifier and a method of modifying taste | SAN EI GEN FFI INC (JP) | 1999-09-15 | — | — | EP | claimed |
| US-5580545-A | ADDING FLAVONE DERIVATIVES TO FOODS, BEVERAGES OR TOILETRIES TO ENHANCE OR REDUCE FLAVORS | SAN-EI GEN F.F.I., INC. (JP) | 1996-12-03 | — | — | US | claimed |
| EP-0605261-A2 | A taste modifier and a method of modifying taste | SAN-EI GEN F.F.I., INC. (JP) | 1994-07-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050249803-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | TTPA, CCNE2, PTGES | ALDH1A1 2980/4885MEN1 2329/4885KMT2A 767/4885 |
| US-20060003947-A1 | Soft gel capsules containing polymethoxylated flavones and palm oil tocotrienols | TTPA, PLA2G10, GSTO1 | ALDH1A1 1764/4885MEN1 3026/4885KMT2A 1236/4885 |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | CYP2D6, GATAD2A, CYP3A43 | ALDH1A1 668/4885MEN1 3778/4885KMT2A 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.