Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27584329 | 0.95 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1PARP1ALOX15BDKRB1 | |
| SCHEMBL6366673 | 0.83 | NR4A1 (0.54) | ALDH1A1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3446883 | 0.81 | PARP1 (0.59) | ALDH1A1L3MBTL1PARP1ALOX15BDKRB1 | |
| SCHEMBL6374034 | 0.79 | RECQL (0.50) | ALDH1A1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL28750153 | 0.79 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPTLMNAKEAP1 | |
| SCHEMBL308358 | 0.78 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1MAPTLMNAKEAP1 | |
| SCHEMBL3173817 | 0.76 | PARP1 (0.68) | ALDH1A1L3MBTL1PARP1ALOX15MAPT | |
| SCHEMBL3179857 | 0.76 | RECQL (0.57) | ALDH1A1PARP1ALOX15BDKRB1MAPT | |
| SCHEMBL27584330 | 0.76 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPTLMNAKEAP1 | |
| SCHEMBL6341269 | 0.75 | RECQL (0.60) | ALDH1A1PARP1ALOX15MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | HUANG HSU-SHAN (TW) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | NFE2L2, NR2F2, TFAM | ALDH1A1 692/4885L3MBTL1 301/4885PARP1 2470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.