SCHEMBL2454845

SCHEMBL2454845

N#CC(CCCCc1ccccc1)OC(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
TRPA1 O75762 1/20 0.43
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
SLC6A3 Q01959 2/20 0.41
MAPT P10636 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
SLC6A2 P23975 1/20 0.41
KMT2A Q03164 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
CYP2D6 P10635 1/20 0.41
CTSC P53634 1/20 0.40
HDAC1 Q13547 2/20 0.40
HDAC3 O15379 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8662418 0.99 TRPA1 (0.45) TDP1NPC1RAB9ACASP3SENP8
SCHEMBL11303515 0.96 TDP1 (0.45) TDP1NPC1RAB9ACASP3SENP8
SCHEMBL16672635 0.82 NAAA (0.53) TDP1NPC1RAB9ACASP3SENP8
SCHEMBL6367353 0.82 CYP2D6 (0.50) TDP1RAB9ATP53TSHRSLC6A3
SCHEMBL31439099 0.79 PRKCA (0.48) TDP1NPC1RAB9ACASP3SENP8
SCHEMBL14297465 0.77 TP53 (0.46) TDP1NPC1RAB9ACASP3SENP8
SCHEMBL16673398 0.75 ALDH1A1 (0.47) TDP1NPC1RAB9ATP53TSHR
SCHEMBL5165238 0.75 AKR1B10 (0.52) KMT2AMAPK1
SCHEMBL7693931 0.75 MMP12 (0.49) TSHRKMT2ACTSCSMN1; SMN2
SCHEMBL4051389 0.75 CTSC (0.46) TSHRKMT2ACTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12292665-B2 Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof GAUZY LTD. (IL) 2025-05-06 US disclosed
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 US disclosed
US-20170336663-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2017-11-23 US disclosed
EP-0179903-A4 LIQUID CRYSTAL PROJECTOR AND METHOD. MANCHESTER R & D PARTNERSHIP (US) 1987-10-20 EP disclosed
EP-0214242-A1 LIQUID CRYSTAL COLOR DISPLAY AND METHOD. MANCHESTER R & D PARTNERSHIP (US) 1987-03-18 EP disclosed
US-4643528-A Encapsulated liquid crystal and filler material MANCHESTER R & D PARTNERSHIP (US) 1987-02-17 US disclosed
US-4616903-A Encapsulated liquid crystal and method MANCHESTER R & D PARTNERSHIP (US) 1986-10-14 US disclosed
WO-1986005282-A1 LIQUID CRYSTAL COLOR DISPLAY AND METHOD MANCHESTER R & D PARTNERSHIP (US) 1986-09-12 WO disclosed
EP-0179903-A1 LIQUID CRYSTAL PROJECTOR AND METHOD. MANCHESTER R & D PARTNERSHIP (US) 1986-05-07 EP disclosed
WO-1985005192-A1 LIQUID CRYSTAL PROJECTOR AND METHOD MANCHESTER R & D PARTNERSHIP (US) 1985-11-21 WO disclosed
WO-1985003944-A1 ENCAPSULATED LIQUID CRYSTAL MATERIAL, APPARATUS AND METHOD MANCHESTER R & D PARTNERSHIP (US) 1985-09-12 WO disclosed
US-4265784-A Azine liquid crystal compounds for use in light-control devices GENERAL ELECTRIC COMPANY (US) 1981-05-05 US disclosed
US-4196975-A Azine liquid crystal compounds for use in light-control devices GENERAL ELECTRIC COMPANY (US) 1980-04-08 US disclosed