Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834728 | 0.89 | KDM4E (0.50) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1931554 | 0.83 | ALDH1A1 (0.44) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL29853841 | 0.81 | TSHR (0.45) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL488963 | 0.81 | TSHR (0.45) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1931552 | 0.76 | CYP3A4 (0.36) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL14639002 | 0.76 | CYP2C19 (0.49) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL10488213 | 0.75 | CYP1A2 (0.40) | KMT2ACYP1A2TSHR | |
| SCHEMBL31283575 | 0.75 | CYP3A4 (0.50) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL488903 | 0.75 | CYP3A4 (0.50) | KDM4ECYP3A4MAPTMEN1KMT2A | |
| SCHEMBL713198 | 0.74 | HTR2A (0.54) | KDM4ECYP3A4MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310333-A1 | MESOPOROUS SILICA NANOPARTICLE CONTROLLED RELEASE SYSTEM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-10-05 | — | — | US | disclosed |
| US-20230310333-A1 | MESOPOROUS SILICA NANOPARTICLE CONTROLLED RELEASE SYSTEM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-10-05 | — | — | US | disclosed |
| EP-4209230-A1 | MESOPOROUS SILICA NANOPARTICLE CONTROLLED RELEASE SYSTEM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | East China University of Science and Technology (CN) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022048470-A1 | MESOPOROUS SILICA NANOPARTICLE CONTROLLED RELEASE SYSTEM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 华东理工大学 | 2022-03-10 | — | — | WO | disclosed |
| US-6916660-B2 | Fluorescent sensor compounds for detecting saccharides | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-07-12 | — | — | US | disclosed |
| US-6804544-B2 | GLUCOSE MEASUREMENT | MINIMED, INC. | 2004-10-12 | — | — | US | disclosed |
| EP-0862648-B1 | DETECTION OF BIOLOGICAL MOLECULES USING CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | MEDTRONIC MINIMED INC (US) | 2004-10-06 | — | — | EP | disclosed |
| US-6750311-B1 | CONCENTRATION OF BLOOD GLUCOSE; BORONATE COMPLEX WITH A FLUORESCENT DYE; POLYURETHANE OR POLYUREA BIOCOMPATABLE MATRIX BY REACTION OF A DIISOCYANATE WITH A POLYMERIC DIOL OR POLYMERIC DIAMINE | MINIMED INC. | 2004-06-15 | — | — | US | disclosed |
| US-20040048390-A1 | Fluorescent sensor compounds for detecting saccharides | NORTH CAROLINA STATE UNIVERSITY | 2004-03-11 | — | — | US | disclosed |
| US-20020018843-A1 | Detection of biological molecules using chemical amplification and optical sensors | MINIMED INC. | 2002-02-14 | — | — | US | disclosed |
| US-6319540-B1 | IMMOBILIZING BORONIC ACID MOIETY IN SOLID SUPPORT BY ATTACHING TO A POLYMER MATRIX | MINIMED INC. | 2001-11-20 | — | — | US | disclosed |
| US-6011984-A | Detection of biological molecules using chemical amplification and optical sensors | MINIMED INC. (US) | 2000-01-04 | — | — | US | disclosed |
| US-6002954-A | IMPLANTABLE AMPLIFICATION SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1998022820-A9 | DETECTION OF BIOLOGICAL MOLECULES USING BORONATE-BASED CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | — | 1998-09-11 | — | — | WO | disclosed |
| EP-0862648-A1 | DETECTION OF BIOLOGICAL MOLECULES USING CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | Minimed Inc. (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1998022820-A1 | DETECTION OF BIOLOGICAL MOLECULES USING BORONATE-BASED CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | LAWRENCE LIVERMORE NATIONAL LABORATORY (US) | 1998-05-28 | — | — | WO | disclosed |
| WO-1997019188-A1 | DETECTION OF BIOLOGICAL MOLECULES USING CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | MINIMED, INC. (US) | 1997-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230310333-A1 | MESOPOROUS SILICA NANOPARTICLE CONTROLLED RELEASE SYSTEM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SUCNR1, GOT1, BPGM | KDM4E 3079/4885CYP3A4 1103/4885MAPT 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.