Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853841 | 1.00 | TSHR (0.45) | TSHRCYP2A6APOBEC3GIDO1GABRA1 | |
| SCHEMBL14008502 | 0.89 | MEN1 (0.41) | TSHRCYP2A6APOBEC3GIDO1HSD17B10 | |
| SCHEMBL1072230 | 0.87 | DRD4 (0.37) | TSHRCYP2A6APOBEC3GIDO1GABRA1 | |
| SCHEMBL2397625 | 0.87 | MAOA (0.41) | TSHRCYP2A6APOBEC3GIDO1GABRA1 | |
| SCHEMBL31283575 | 0.87 | CYP3A4 (0.50) | TSHRCYP2A6APOBEC3GGABRA1GABRG2 | |
| SCHEMBL488903 | 0.87 | CYP3A4 (0.50) | TSHRCYP2A6APOBEC3GGABRA1GABRG2 | |
| SCHEMBL59671 | 0.81 | HTR2A (0.60) | HSD17B10CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL29367221 | 0.81 | HTR2A (0.60) | HSD17B10CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL392193 | 0.81 | KDM4E (0.39) | TSHRCYP2A6APOBEC3GIDO1HSD17B10 | |
| SCHEMBL6367803 | 0.81 | KDM4E (0.41) | TSHRCYP2A6IDO1GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805561-B1 | ANTIREFLECTIVE COMPOSITIONS FOR PHOTORESISTS | MERCK PATENT GMBH (DE) | 2018-10-24 | — | — | EP | claimed |
| US-8105836-B2 | Chemical inhibitors of mismatch repair | MORPHOTEK, INC. (US) | 2012-01-31 | — | — | US | claimed |
| EP-1351565-B1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC (US) | 2011-03-16 | — | — | EP | claimed |
| US-6982169-B2 | Chemical inhibitors of mismatch repair | MORPHOTEK, INC. (US) | 2006-01-03 | — | — | US | claimed |
| EP-1351565-A4 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1417329-A4 | METHODS FOR GENERATING ANTIBIOTIC RESISTANT MICROBES AND NOVEL ANTIBIOTICS | MORPHOTEK INC (US) | 2005-05-11 | — | — | EP | claimed |
| EP-1417329-A1 | METHODS FOR GENERATING ANTIBIOTIC RESISTANT MICROBES AND NOVEL ANTIBIOTICS | Morphotek Inc. (US) | 2004-05-12 | — | — | EP | claimed |
| EP-1351565-A1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | Morphotek Inc. (US) | 2003-10-15 | — | — | EP | claimed |
| US-20030143586-A1 | Genetic hypermutability of plants for gene discovery and diagnosis | MORPHOTEK, INC. | 2003-07-31 | — | — | US | claimed |
| US-20030091997-A1 | Chemical inhibitors of mismatch repair | EISAI, INC. | 2003-05-15 | — | — | US | claimed |
| WO-2003031937-A2 | GENETIC HYPERMUTABILITY OF PLANTS FOR GENE DISCOVERY AND DIAGNOSIS | MORPHOTEK, INC. (US) | 2003-04-17 | — | — | WO | claimed |
| US-20030068808-A1 | Methods for generating antibiotic resistant microbes and novel antibiotics | MORPHOTEK, INC. | 2003-04-10 | — | — | US | claimed |
| US-6544717-B2 | Antireflective coating | TOKYO OHKA KOGYO CO., LTD. (JP) | 2003-04-08 | — | — | US | claimed |
| WO-2003012130-A1 | METHODS FOR GENERATING ANTIBIOTIC RESISTANT MICROBES AND NOVEL ANTIBIOTICS | MORPHOTEK INC. (US) | 2003-02-13 | — | — | WO | claimed |
| WO-2002054856-A1 | CHEMICAL INHIBITORS OF MISMATCH REPAIR | MORPHOTEK INC. (US) | 2002-07-18 | — | — | WO | claimed |
| US-20010018163-A1 | Undercoating composition for photolithographic resist | TOKYO OHKA KOGYO CO., LTD. (JP) | 2001-08-30 | — | — | US | claimed |
| EP-4091578-B1 | METHOD FOR PRODUCING PLATE DENTURE | TOKUYAMA DENTAL CORP (JP) | 2024-10-09 | — | — | EP | disclosed |
| US-11857385-B2 | Method of producing plate denture, curable composition for stereolithography, and plate denture production kit | TOKUYAMA DENTAL CORPORATION (JP) | 2024-01-02 | — | — | US | disclosed |
| US-6284428-B1 | FOR FORMING OF ANTIREFLECTION UNDERCOATING LAYER TO INTERVENE BETWEEN SURFACE OF SUBSTRATE AND PHOTORESIST LAYER TO BE PATTERNED IN MANUFACTURING PROCESS OF SEMICONDUCTOR DEVICES | TOKYO OHKA KOGYO CO., LTD, (JP) | 2001-09-04 | — | — | US | disclosed |
| US-20010018163-A1 | Undercoating composition for photolithographic resist | TOKYO OHKA KOGYO CO., LTD. (JP) | 2001-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030091997-A1 | Chemical inhibitors of mismatch repair | MSH2, MSH6, PMS2 | TSHR 4665/4885CYP2A6 2364/4885APOBEC3G 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.