SCHEMBL6368100

SCHEMBL6368100

Cc1cc(C)c(-c2nc3cccc(C)c3[nH]2)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
HPGD P15428 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
HTT P42858 1/20 0.42
CRHR1 P34998 1/20 0.38
CYP3A4 P08684 1/20 0.37
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
DGAT1 O75907 1/20 0.36
PARP1 P09874 1/20 0.36
DAO P14920 1/20 0.35
DDO Q99489 1/20 0.35
PDE3B Q13370 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13405987 0.80 GUSB (0.53) ALDH1A1NPC1RAB9AHPGDSMN1; SMN2
SCHEMBL6368223 0.80 KDM4E (0.39) ALDH1A1NPC1RAB9AHPGDSMN1; SMN2
SCHEMBL3539421 0.80 ADORA2B (0.43) ALDH1A1NPC1RAB9AHPGDSMN1; SMN2
SCHEMBL13406019 0.79 ALDH1A1 (0.55) ALDH1A1NPC1RAB9AHPGDSMN1; SMN2
SCHEMBL12636735 0.78 TNKS (0.54) ALDH1A1NPC1RAB9AHPGDSMN1; SMN2
SCHEMBL6759201 0.78 ALDH1A1 (0.60) ALDH1A1NPC1RAB9AHPGDSMN1; SMN2
SCHEMBL13405986 0.78 NQO2 (0.46) ALDH1A1NPC1RAB9AHPGDSMN1; SMN2
SCHEMBL29268851 0.78 HPGD (0.41) ALDH1A1NPC1RAB9AHPGDSMN1; SMN2
SCHEMBL13405981 0.77 NPC1 (0.69) ALDH1A1NPC1RAB9AHPGDSMN1; SMN2
SCHEMBL2578466 0.77 NPC1 (0.46) ALDH1A1NPC1RAB9AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0562187-B1 Process for production of copper through-hole printed wiring boards SANWA LAB LTD (JP) 1996-01-10 EP claimed
EP-0562187-A1 Process for production of copper through-hole printed wiring boards SANWA LABORATORY LTD. (JP) 1993-09-29 EP claimed
EP-0428260-A2 Metal surface treatment agents SANWA LABORATORY LTD. (JP) 1991-05-22 EP claimed
US-20050173678-A1 Surface treatment agents for metal films of printed circuit boards TAMURA KAKEN CORPORATION (JP) 2005-08-11 US disclosed
US-6712262-B2 BENZIMIDAZOLE AND IODINE COMPOUNDS TAMURAKAKEN CORPORATION (JP) 2004-03-30 US disclosed
US-20030141351-A1 Water-soluble preflux, printed circuit board, and process for treating the surface of a metal in a printed circuit board TAMURA CORPORATION (JP) 2003-07-31 US disclosed
EP-0428260-A2 Metal surface treatment agents SANWA LABORATORY LTD. (JP) 1991-05-22 EP disclosed