Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CBFB | Q13951 | 3/20 | 0.41 |
| ▸ | METAP2 | P50579 | 3/20 | 0.41 |
| ▸ | METAP1 | P53582 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405981 | 0.81 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12834347 | 0.80 | ADORA3 (0.66) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL6368201 | 0.80 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL14091330 | 0.79 | METAP2 (0.46) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12833521 | 0.79 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12636735 | 0.79 | TNKS (0.54) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL3539421 | 0.77 | ADORA2B (0.43) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL13405987 | 0.77 | GUSB (0.53) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL5201211 | 0.77 | GAA (0.58) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL6368100 | 0.77 | ALDH1A1 (0.42) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049117-B1 | Ruthenium complex dye | FUJIFILM CORP (JP) | 2011-11-02 | — | — | EP | disclosed |