SCHEMBL6368591

SCHEMBL6368591

O=C(c1c(Cl)cccc1Cl)P(=O)(O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
PTK2B Q14289 1/20 0.46
ALDH1A1 P00352 3/20 0.45
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA5A P35218 1/20 0.43
FEN1 P39748 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
CFTR P13569 1/20 0.39
PBRM1 Q86U86 1/20 0.39
ACP3 P15309 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
TAS1R2 Q8TE23 1/20 0.38
KDM4E B2RXH2 1/20 0.38
APAF1 O14727 1/20 0.38
TDP2 O95551 1/20 0.38
NSD2 O96028 1/20 0.38
ABL1 P00519 1/20 0.38
GALK1 P51570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67557 0.83 ALDH1A1 (0.47) MAPTPTK2BALDH1A1CA2CA4
SCHEMBL58730 0.83 ALDH1A1 (0.47) MAPTPTK2BALDH1A1CA2CA4
SCHEMBL7189912 0.80 ALDH1A1 (0.44) MAPTPTK2BALDH1A1CA2CA4
SCHEMBL10954791 0.78 ALDH1A1 (0.45) MAPTPTK2BALDH1A1CA2CA4
SCHEMBL6364041 0.78 CA2 (0.43) ALDH1A1CA2CA4CA5ACFTR
SCHEMBL7179365 0.77 ALDH1A1 (0.41) MAPTPTK2BALDH1A1CA2CA4
SCHEMBL2771878 0.76 MAPT (0.42) MAPTPTK2BALDH1A1FEN1PBRM1
SCHEMBL7188567 0.76 ALDH1A1 (0.40) MAPTPTK2BALDH1A1FEN1PBRM1
SCHEMBL7189823 0.76 TSHR (0.41) MAPTPTK2BALDH1A1CA2CA4
SCHEMBL7182200 0.76 ALDH1A1 (0.40) MAPTPTK2BALDH1A1FEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050221210-A1 Electrophotographic photoconductor and image formation method, image formation apparatus, and process cartridge for image formation apparatus using the electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2005-10-06 US disclosed
US-4719297-A Acylphosphine compounds and their use as photoinitiators BASF AKTIENGESELLSCHAFT (DE) 1988-01-12 US disclosed
EP-0062839-B1 ACYLPHOSPHINE COMPOUNDS AND THEIR USE BASF Aktiengesellschaft (DE) 1984-11-21 EP disclosed
EP-0062839-A1 Acylphosphine compounds and their use BASF Aktiengesellschaft (DE) 1982-10-20 EP disclosed