SCHEMBL58730

SCHEMBL58730

O=C(c1c(Cl)cccc1Cl)P(=O)(C(=O)c1c(Cl)cccc1Cl)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
MAPT P10636 2/20 0.44
PTK2B Q14289 1/20 0.44
FEN1 P39748 1/20 0.42
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA5A P35218 1/20 0.40
PBRM1 Q86U86 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
KDM4E B2RXH2 1/20 0.39
APAF1 O14727 1/20 0.39
TDP2 O95551 1/20 0.39
NSD2 O96028 1/20 0.39
ABL1 P00519 1/20 0.39
GALK1 P51570 1/20 0.39
BLM P54132 1/20 0.39
RIN1 Q13671 1/20 0.39
SENP8 Q96LD8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7179365 0.93 ALDH1A1 (0.41) ALDH1A1MAPTPTK2BFEN1CA2
SCHEMBL7183633 0.92 ALDH1A1 (0.40) ALDH1A1MAPTPTK2BFEN1PBRM1
SCHEMBL7189823 0.92 TSHR (0.41) ALDH1A1MAPTPTK2BFEN1CA2
SCHEMBL7180942 0.90 ALDH1A1 (0.39) ALDH1A1MAPTPTK2BFEN1CA2
SCHEMBL7188901 0.90 ALDH1A1 (0.39) ALDH1A1MAPTPTK2BFEN1PBRM1
SCHEMBL7179862 0.90 TYK2 (0.44) ALDH1A1MAPTPTK2BABL1TYK2
SCHEMBL7174811 0.90 TYK2 (0.44) ALDH1A1MAPTPTK2BABL1TYK2
SCHEMBL2770598 0.90 MEN1 (0.47) ALDH1A1MAPTPTK2BFEN1KDM4E
SCHEMBL7180903 0.87 ITGB1 (0.41) ALDH1A1MAPTPTK2BFEN1HPGD
SCHEMBL58229 0.87 ALDH1A1 (0.45) ALDH1A1MAPTPTK2BFEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051500-A1 RADIATION-CURABLE COMPOSITION MARABU GMBH & CO. KG (DE) 2025-02-13 US claimed
EP-4506424-A1 RADIATION-CURABLE COMPOSITION Marabu GmbH & Co. KG (DE) 2025-02-12 EP claimed
US-12024136-B2 Ultra-fast curing scratch-resistant headlight restoration coating ILLINOIS TOOL WORKS INC. (US) 2024-07-02 US claimed
US-20240173212-A1 HIGH TRANSPARENCY AND LONG-RELEASE DENTAL RESIN COMPOSITION CONTAINING CORE-SHELL POROUS STRUCTURED NANOPARTICLES AND METHOD FOR PREPARING THE SAME JNP Nature Co., Ltd. (KR) 2024-05-30 US claimed
CN-118078642-A High-transparency and long-term release dental resin composition comprising core-shell porous structured nanoparticles and method for preparing same JNP自然股份有限公司 2024-05-28 CN claimed
EP-4056658-A1 RADIATION-CURABLE COMPOUND Marabu GmbH & Co. KG (DE) 2022-09-14 EP claimed
EP-0325266-B1 DENTAL MATTER THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) 1993-08-11 EP claimed
EP-0184095-B1 BISACYLPHOSPHINOXIDES, THEIR PREPARATION AND USE ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) 1989-07-05 EP claimed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US claimed
JP-1102455-A None JP disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
US-12617887-B2 Resin composition for stereolithography KURARAY NORITAKE DENTAL INC. (JP) 2026-05-05 US disclosed
EP-3862373-B1 RESIN COMPOSITION FOR OPTICAL SHAPING KURARAY NORITAKE DENTAL INC (JP) 2026-04-22 EP disclosed
EP-0915136-A1 Photocurable paint composition for road markings SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-05-12 EP disclosed
EP-0825201-A1 Photocurable composition and curing process therefor SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-02-25 EP disclosed
US-5472991-A Irradiating curable composition containing unsaturated monomer, fillers, two photoinitiators activated by light of different wavelengths, first at one wavelength, then another 501 ESPE STIFTUNG & CO. PRODUKTIONS-UND (DE) 1995-12-05 US disclosed
US-4868091-A USING A BISACYLPHOSPHINE OXIDE PHOTOINITIATOR, UNSATURATED COMPOUND AND POLYMERIC BINDER; SHORT EXPOSURE TIME; NEWSPAPER PRINTING BASF AKTIENGESELLSCHAFT (DE) 1989-09-19 US disclosed
US-4792632-A ADDITION POLYMER PHOTOINITIATORS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1988-12-20 US disclosed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL ALDH1A1 668/4885MAPT 4304/4885PTK2B 543/4885
US-12617887-B2 Resin composition for stereolithography MAT2B, MAT1A, ARCN1 ALDH1A1 339/4885MAPT 2407/4885PTK2B 2674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.