SCHEMBL6370474

SCHEMBL6370474

CCCCCCCCc1ccc(Cl)c(NC(C)=O)c1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
PLK1 P53350 1/20 0.47
KAT8 Q9H7Z6 2/20 0.47
PPARA Q07869 2/20 0.47
THRA P10827 4/20 0.46
THRB P10828 4/20 0.46
PPARG P37231 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9845820 0.89 PLK1 (0.50) ALDH1A1PLK1KAT8PPARATHRA
SCHEMBL3438737 0.88 POLB (0.55) ALDH1A1PLK1KAT8PPARATHRA
SCHEMBL2748823 0.82 CA1 (0.49) ALDH1A1PLK1
SCHEMBL30667032 0.82 ALDH1A1 (0.59) ALDH1A1MEN1KMT2A
SCHEMBL14405814 0.82 ALDH1A1 (0.59) ALDH1A1MEN1KMT2A
SCHEMBL3656736 0.81 MTNR1A (0.47) ALDH1A1MEN1KMT2A
SCHEMBL27780336 0.80 KAT8 (0.47) PLK1KAT8PPARATHRATHRB
SCHEMBL5968080 0.79 HTR2A (0.47) ALDH1A1KAT8PPARA
SCHEMBL8044551 0.79 HTR2A (0.47) ALDH1A1KAT8PPARA
SCHEMBL11517885 0.78 PGK1 (0.45) ALDH1A1PLK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919297-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2005-07-19 US disclosed
US-20030118851-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-06-26 US disclosed