SCHEMBL8044551

SCHEMBL8044551

CCCCCCCCCCCCCCCCc1ccc(Cl)c(NN)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.47
ESR1 P03372 2/20 0.43
ADRA2A P08913 2/20 0.43
ADORA3 P0DMS8 2/20 0.43
TACR2 P21452 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
SHBG P04278 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
HSPD1 P10809 1/20 0.43
ADRB3 P13945 1/20 0.43
HTR2C P28335 1/20 0.43
HSPE1 P61604 1/20 0.43
HIF1A Q16665 1/20 0.43
TST Q16762 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5968080 1.00 HTR2A (0.47) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL22333700 0.79 SIGMAR1 (0.61) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL11066232 0.79 SIGMAR1 (0.61) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL6370474 0.79 ALDH1A1 (0.48) ALDH1A1KAT8PPARA
SCHEMBL9845820 0.79 PLK1 (0.50) ALDH1A1KAT8PPARA
SCHEMBL6548828 0.78 HTR2A (0.52) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL1448394 0.77 SIGMAR1 (0.63) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL3438737 0.76 POLB (0.55) ALDH1A1KAT8PPARA
SCHEMBL24454689 0.75 HTR2A (0.52) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL11205585 0.75 SKP2 (0.56) HTR2AESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0236986-B2 Processing method of light-sensitive silver halide photographic material having good color reproducibility and whiteness KONISHIROKU PHOTO IND (JP) 2000-10-04 EP disclosed
EP-0255292-B1 Processing solution of light-sensitive silver halide color photographic material and processing method of the same KONISHIROKU PHOTO IND (JP) 1994-05-11 EP disclosed
US-4948713-A AS PRESERVATIVE AN N-ALKOXYALKYL-HYROXYLAMINE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1990-08-14 US disclosed
US-4837139-A ORGANIC HYDROXYLAMINE PRESERVATIVE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-06-06 US disclosed
EP-0236986-A2 Processing method of light-sensitive silver halide photographic material having good color reproducibility and whiteness KONICA CORPORATION (JP) 1987-09-16 EP disclosed