Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.37 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370115 | 0.89 | FTO (0.47) | PLK1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL6276352 | 0.86 | KDM4C (0.45) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL6269745 | 0.85 | KDM4E (0.48) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL6365203 | 0.74 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL6364445 | 0.74 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL28642791 | 0.71 | PLK1 (0.44) | PLK1SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL6369492 | 0.70 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6370612 | 0.70 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL22189692 | 0.69 | L3MBTL1 (0.56) | SLC6A4SLC6A3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6869843 | 0.68 | KDM4C (0.49) | MEN1KMT2AKDM4CKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026920-A1 | Selective serotonin re-uptake inhibitors; use in treatment of depression, attention deficit hyperactivity disorder, obsessive-compulsive disorder, post-traumatic stress disorder, substance abuse disorders and sexual dysfunction | PFIZER INC | 2005-02-03 | — | — | US | disclosed |
| US-6800652-B2 | SELECTIVE SEROTONIN RE-UPTAKE INHIBITORS | PFIZER INC. | 2004-10-05 | — | — | US | disclosed |
| US-20040097509-A1 | Diaryl compounds | PFIZER INC. | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097509-A1 | Diaryl compounds | CCNL2, CCNI, CCNA1 | PLK1 2333/4885SLC6A4 1969/4885SLC6A2 1307/4885 |
| US-20050026920-A1 | Selective serotonin re-uptake inhibitors; use in treatment of depression, attention deficit hyperactivity disorder, obsessive-compulsive disorder, post-traumatic stress disorder, substance abuse disorders and sexual dysfunction | SLC6A4, SLC6A2, SLC6A3 | PLK1 2562/4885SLC6A4 1/4885SLC6A2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.