SCHEMBL6370786

SCHEMBL6370786

CCCCCCCCCCCCCCCCCC(C(F)(F)N=C=O)C(F)(F)N=C=O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
FAAH O00519 7/20 0.33
CES1 P23141 5/20 0.33
FDPS P14324 4/20 0.33
GPR84 Q9NQS5 3/20 0.33
CES2 O00748 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
FFAR1 O14842 1/20 0.33
LCK P06239 1/20 0.32
PPARD Q03181 1/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6367143 0.76
SCHEMBL6370817 0.75 MAPT (0.38) MAPTFAAHCES1FDPSGPR84
SCHEMBL8588299 0.71 LMNA (0.42) MAPTFAAHCES1FDPSGPR84
SCHEMBL13557036 0.71 LMNA (0.42) MAPTFAAHCES1FDPSGPR84
SCHEMBL4652996 0.71 LMNA (0.42) MAPTFAAHCES1FDPSGPR84
Octane SCHEMBL9437891 0.69 TSHR (0.40) MAPTFAAHCES1CES2MEN1
SCHEMBL9148426 0.68 OPRM1 (0.42) MAPTFAAHCES1FDPSGPR84
SCHEMBL25170599 0.68 MAPT (0.34) MAPTFDPSGPR84FFAR1LCK
SCHEMBL25176247 0.68 MAPT (0.34) MAPTFDPSGPR84FFAR1LCK
SCHEMBL25173775 0.68 MAPT (0.34) MAPTFDPSGPR84FFAR1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050131192-A1 Polymer and process for producing polymer SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-06-16 US disclosed