SCHEMBL6370817

SCHEMBL6370817

CCCCCCCCCCCCCCCC(C(F)(F)CN=C=O)C(F)(F)CN=C=O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.38
GPR84 Q9NQS5 7/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33
FDPS P14324 4/20 0.32
FAAH O00519 6/20 0.32
CES1 P23141 4/20 0.32
CES2 O00748 1/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
FFAR1 O14842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6366379 0.77
SCHEMBL6370786 0.75 MAPT (0.40) MAPTGPR84FDPSFAAHCES1
SCHEMBL12096800 0.70 LPAR1 (0.46) LPAR1LPAR3FDPSFAAHCES1
SCHEMBL12096933 0.70 LPAR1 (0.46) LPAR1LPAR3FDPSFAAHCES1
SCHEMBL13557036 0.68 LMNA (0.42) MAPTGPR84FDPSFAAHCES1
SCHEMBL4652996 0.68 LMNA (0.42) MAPTGPR84FDPSFAAHCES1
SCHEMBL8588299 0.68 LMNA (0.42) MAPTGPR84FDPSFAAHCES1
SCHEMBL15087070 0.67 LMNA (0.38) MAPTGPR84LPAR1LPAR3FDPS
SCHEMBL13069624 0.67 NAAA (0.47) MAPTGPR84FDPSMEN1KMT2A
SCHEMBL1123429 0.67 NAAA (0.47) MAPTGPR84FDPSMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050131192-A1 Polymer and process for producing polymer SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-06-16 US disclosed